Hi @ladyplumber7 Having osteoporosis shouldn’t effect your having a bone marrow biopsy. I know, it does sound barbaric having a needle inserted into a bone. But the bone marrow biopsy and exam (BMBX) can be a valuable tool for your doctor in determining the health of your bone marrow and its ability to produce healthy blood cells. They’re not done needlessly. Nicer if “needlelessly”. ☺️

The bone marrow is the heart of the blood manufacturing site in the body which makes it the best source for accurate information on the blood cells. The results can show the types of cells, the genetic composition, extent of a disease, etc..

~A possible alternative for a bone marrow biopsy that your doctors may consider if it’s out of the question for you to have a BMBX. Blood work, along with Next-generation sequencing (NGS) has been shown to offer results on par with a BMBX. Talk it over with your doctor.

You mentioned that you’re allergic to anything in the ‘caine’ family of anesthetics. Not every anesthetic that ends in ‘caine’ are from the same class of drugs though. There are alternative local anesthetics to drugs from the Lidocaine line (that still may end in ‘caine’. In the dental practice where I worked, we had a couple of patients allergic to Lidocaine. We had other numbing medications we could substitute that worked well with no side effects.
Here is an article that helps explain what I’m talking about.
From Clinical Advisor: https://www.clinicaladvisor.com/features/alternative-treatments-for-patients-with-lidocaine-allergies/

~Also, in larger medical settings a BMBX can be offered under IV sedation. That’s my preferred route to take having had 13 BMBXs over the years.

You mentioned in another reply that you were having a 2nd opinion at F Hutch. That is an outstanding medical facility specializing in blood diseases. If you don’t mind sharing, what was the outcome of your visit with them?