1. < Head & Neck Cancer
Profile picture for ja963

Negative NavDx Pre Treatment HPV16 Squamous Cell Cervical Lymph Node

Posted by ja963 @ja963, Aug 6, 2025

Has anyone had a Negative NavDx Pre Treatment of HPV16 Squamous Cell Cervical Lymph Node.?
As well as unknown primary source?
If you the primary source was "known", feel free to answer.

Interested in more discussions like this? Go to the Head & Neck Cancer Support Group.

Profile picture for judiroe
judiroe | @judiroe | Aug 2 4:42pm
In reply to @ja963 "@judiroe Hello, Not sure if you are still following. But did they find primary pathology?" + (show)
Profile picture for ja963 @ja963

@judiroe Hello, Not sure if you are still following. But did they find primary pathology?

Jump to this post

@ja963 I am still here. No primary has been found. Tonsil was negative. A neck dissection the next month found no cancer cells, so I went on a 3 month follow up & November will be my 6 month follow scan. At 3 months I had a NavDX blood test which was also negative.

REPLY
Profile picture for roblem
roblem | @roblem | Aug 3 1:17pm
In reply to @edelec40 "I have not had treatment but was diagnosed last year with P16 left tounsular Squamous head..." + (show)
Profile picture for edelec40 @edelec40

I have not had treatment but was diagnosed last year with P16 left tounsular Squamous head neck cancer.
I had Keytruda immunology , worked for a while and then became in effective . Looking for healthy options , I have learned that an MRI with non radio active contrast , weather local or whole body is a healthier option versus ionizing radiation , Natera blood biopsy is another healthier option versus removing tissue from the tumor outer protective cover. I also have had a genomic tumor profile , and found I lack tumor suppressors and will research PTEN and other therapies for reducing tumor size , if this interests you , tell you Dr , it is not standard care, and you need to self advocate these options. I have also used Galleri blood testing to see if cancer DNA maybe present in other areas. Anyone with tumor suppressor/ reducers please advise

Jump to this post

Hi @edelec40
Does the Galleri blood test tell you if it does show cancer tell you the location of it?

REPLY
Profile picture for edelec40
edelec40 | @edelec40 | Aug 5 8:42am

The Galleri Blood test checks for the presence on cancer DNA , and to date I have only found Brigham Hospital in Mass has an early detection clinic that will accept the results , if you do go this route and they do detect a cancer , it will tell you what area, give you a percentile, and if it detects cancer they will give you a free retest. You will need to pay about $900 out of pocket for the test

REPLY
Profile picture for sandy8043
sandy8043 | @sandy8043 | 1 day ago

My pre surgery Natera test was negative. Mayo team was not concerned by that. They said they send the tumor sample DNA to Natera for future testing comparisons. So Natera has my cancer on file. So all post surgical tests are compared to that tumor sample. I have to say it concerned and confused me at first. But there seem to be a lot of things about cancer that I've learned to take on faith. This is one of them.

REPLY
Please sign in or register to post a reply.