Aromatase Inhibitors: Did you decide to go on them or not?

Posted by nanato6 @nanato6, Oct 12, 2018

Nanaloves: I’m about to start arimidex and just feel that the contraindications , bone issues etc. are overwhelming. I’m 70 years old, dodged a bullet I feel with zero stage DCIS but the follow up is pretty much no different then if it was more aggressive. I’ve just done 33 treatments of radiation and now they advise arimidex as a preventative. I’m not sure with the beginnings of arthritis and lower back. sensitivity already that I should take it. Anyone not take it and not have a recurrence within the 5 years.

Interested in more discussions like this? Go to the Breast Cancer Support Group.

Profile picture for callalloo @callalloo

Trigger Finger and heightened risk for Carpal Tunnel Syndrome are both a submenu, in a sense, of the arthralgia side effects of aromatase inhibitors. One study noted their frequency and that they might be being overlooked by patients as arthritis or general 'aging.'
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Increased Risk of Carpal Tunnel Syndrome and Trigger Finger in Women Using Aromatase Inhibitor Medications

CONCLUSION: Our study demonstrates that females who used AI medication were at increased risk of developing CTS or TF within 1 year of use. 
https://meeting.handsurgery.org/abstracts/2020/HS25.cgi
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Incidence and Treatment Efficacy of Trigger Finger in the Breast Cancer Population on Aromatase Inhibitors

Conclusions: This study demonstrates for the first time the incidence, treatment outcomes, and surgical risk factors of trigger finger in patients on AI therapy for breast cancer
https://pubmed.ncbi.nlm.nih.gov/34078170/

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@callalloo thank you for posting about these studies. I’ve been on Letrozole for nearly a year & within the prior month have developed numbness/weakness in my thumb & pointer finger pincer grasp. Over the last two+ weeks this has evolved & worsened to a pain on the underside of my thumb to pain running through the connecting tendon to my finger & my thumb’s knuckle joint “sticking” or “popping.” I need to update my oncologist of the new developments.

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Profile picture for nanato6 @nanato6

Thank you for your quick reply. I also had a lumpectomy with no node involvement. A protein beam wasn’t offered. I didn’t think tamoxifen was an option for us post menopausal gals. I’ll mention that if the other AIs are a problem. Best to you!

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@nanato6 I had stage 2 lobular cancer with no lymph node involvement. Along with the oncologist, I decided against hormone therapy due to my age, almost 80. I was also told that Tamoxifen was not given to postmenopausal women. I had 5 days of radiation, with no side effects or damage to the skin. I recently had a follow-up appointment with my surgeon. He said I would continue to have follow-ups with the breast clinic every 6 months and an annual mammogram. Good luck to you and all of us on this journey.

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Profile picture for angele2times @angele2times

@sboston1
Hi !

Try Propel a water supplement, with electrolytes, works very well with Exemestane, I have had little to no side effects from the Exemestane so far, on since end of March. Try your current drug with that hopefully that will help.
Yes, it is terribly unfair that we have to endure further trauma, after all that we have been through. Hope this works for you.

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@angele2times, did you try it yet?

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