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Aromatase Inhibitors: Did you decide to go on them or not?

Posted by nanato6 @nanato6, Oct 12, 2018

Nanaloves: I’m about to start arimidex and just feel that the contraindications , bone issues etc. are overwhelming. I’m 70 years old, dodged a bullet I feel with zero stage DCIS but the follow up is pretty much no different then if it was more aggressive. I’ve just done 33 treatments of radiation and now they advise arimidex as a preventative. I’m not sure with the beginnings of arthritis and lower back. sensitivity already that I should take it. Anyone not take it and not have a recurrence within the 5 years.

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pam25 | @pam25 | 21 hours ago
In reply to @callalloo "Trigger Finger and heightened risk for Carpal Tunnel Syndrome are both a submenu, in a sense,..." + (show)
Profile picture for callalloo @callalloo

Trigger Finger and heightened risk for Carpal Tunnel Syndrome are both a submenu, in a sense, of the arthralgia side effects of aromatase inhibitors. One study noted their frequency and that they might be being overlooked by patients as arthritis or general 'aging.'
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Increased Risk of Carpal Tunnel Syndrome and Trigger Finger in Women Using Aromatase Inhibitor Medications

CONCLUSION: Our study demonstrates that females who used AI medication were at increased risk of developing CTS or TF within 1 year of use. 
https://meeting.handsurgery.org/abstracts/2020/HS25.cgi
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Incidence and Treatment Efficacy of Trigger Finger in the Breast Cancer Population on Aromatase Inhibitors

Conclusions: This study demonstrates for the first time the incidence, treatment outcomes, and surgical risk factors of trigger finger in patients on AI therapy for breast cancer
https://pubmed.ncbi.nlm.nih.gov/34078170/

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@callalloo thank you for posting about these studies. I’ve been on Letrozole for nearly a year & within the prior month have developed numbness/weakness in my thumb & pointer finger pincer grasp. Over the last two+ weeks this has evolved & worsened to a pain on the underside of my thumb to pain running through the connecting tendon to my finger & my thumb’s knuckle joint “sticking” or “popping.” I need to update my oncologist of the new developments.

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