Side Effects of Evenity?

Posted by bradford14design @bradford14design, Nov 4, 2024

I had my 11th injection of Evenity last week. I asked the nurse if any other patients receiving Evenity complained of side effects. He said no. I find this very hard to belive. Would love to hear from those who have experienced side effects.
Mine were mostly felt 12 days after the shots.
Foggy brain for 2-3 days
Low energy
Off balance
Sleep issues
Itchy arms- one time after shot
Red face- a few hours after the shot

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Profile picture for jolie2525 @jolie2525

I’m so scared to take medication because with my bad back, I’d get a side effect. Haven’t fractured and didn’t even when I fell. My dexa did increase from-4.2 to -4 in a year.

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@jolie2525 Those are very low scores. Please see an endocrinologist.

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My dexa score is3.2 it actually got better two years ago3.3 . Before that it’s been the same for 5 years, I’m 70 now.Looking for advice , I’m taking vitamins, don’t want to take medication hope I’m not making wrong decisions.

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Profile picture for windyshores @windyshores

@jolie2525 it sure would seem that you need medication. I have "bad luck" with just about every medication but Tymlos worked for me. I tried a full dose and could not tolerate it, so used the adjustable dosing on the pen to start at 25% dose and moved up to almost a full dose. I have several fractures and come on here to tell people they can be painful and disabling. I was literally crawling on the floor, and even 4 years later, cannot lift much, which means I have lost some independence. Forteo is similar to Tymlos but lower dose. Evenity is very potent and most people seem to do fine on it. I hope you will try a medication! If not, maybe a physical therapist could work with you on avoiding fractures. Still, at the -4 range, thre is danger in sneezing and hugging!

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@windyshores is Evenity more potent or stronger than Tymlos? I’m thinking maybe I should begin it again at a lower dose then increase vs going
On Evenity?

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Profile picture for lynmarie56 @lynmarie56

My dexa score is3.2 it actually got better two years ago3.3 . Before that it’s been the same for 5 years, I’m 70 now.Looking for advice , I’m taking vitamins, don’t want to take medication hope I’m not making wrong decisions.

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@lynmarie56 DEXA machines have a margin of error. The difference between a -3.2 and -3.3 score is most likely due to that margin of error, and, unfortunately, not an improvement. Both scores put you in the "severe osteoporosis" category. I really recommend you seeing an endocrinologist. At 60, my spine dexa score was -3.1. After 1 months of Tymlos, it was -2.4. That's a 10%+ improvement. I do a lot of exercises too but there is no way exercise (or diet) alone could give me the same improvement. My doctor says every untreated person who fractures regrets they were not on medication. The medications are not as bad as many people on these forums talk about. Most people who have no side-effects do not go on these forums for help because they are fine. I had no side effects from my medication. Best wishes to you.

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Oh yes! The weight gain is real as well as fatigue and general lack of strength and energy. I’m usually a very active person, but during the day, I’m having to push myself to get things done. And I’m getting my 6th injection next week. I wouldn’t complain about my weight but combined with the general malaise, it’s a downer. Like I’ve said, if it’s working, I will figure out something concerning my weight (midsection). But it’s difficult to find clothing that still fits.

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I've often wondered what percentage of people have the serious or seriously annoying side effects. It feels like there must be many as not many on Mayo Connect report good success with minimal side effects.
I finished my last (all 12) Evenity 5 weeks ago. In general, I had minimal side effects, some bone and muscle pain - but manageable with minimal motrin and mostly during the earlier months. It would pop up now and then the last 6. And in the first 4-6 months, I would get acid indigestion ...would start on day 10, randomly occur for 10 days, and stop until the next injection. Go figure! At the injection site, arms, I would get slight swelling for about 24 hours. Mostly the effects were just annoying and sometimes fatiguing but the results were excellent.
Spine was -3.0, now -2.0, considered a 14.4% growth
Hip was -2.1, now -1.9, a 5% improvement
Did not have comparable markers at the start, but now my P1NP is 36 and CTX is 208. I believe this shows a stable condition.
I'm now in low bone and out of osteoporosis. While my Dr and I had many discussions re follow up with Reclast and Prolia, I started Prolia yesterday. Was not wild about either but acknowledged that I needed to take one or the other.
I'm 77 yrs, and had never taken any osteoporosis drugs (to the Dr dismay) even though I'd been in osteoporosis for over 10 years. In this case waiting for improved drugs was probably prudent! I've never broken bones, I'm active and in good health. The decisions we have to make are tough but important.

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Profile picture for annq @annq

I've often wondered what percentage of people have the serious or seriously annoying side effects. It feels like there must be many as not many on Mayo Connect report good success with minimal side effects.
I finished my last (all 12) Evenity 5 weeks ago. In general, I had minimal side effects, some bone and muscle pain - but manageable with minimal motrin and mostly during the earlier months. It would pop up now and then the last 6. And in the first 4-6 months, I would get acid indigestion ...would start on day 10, randomly occur for 10 days, and stop until the next injection. Go figure! At the injection site, arms, I would get slight swelling for about 24 hours. Mostly the effects were just annoying and sometimes fatiguing but the results were excellent.
Spine was -3.0, now -2.0, considered a 14.4% growth
Hip was -2.1, now -1.9, a 5% improvement
Did not have comparable markers at the start, but now my P1NP is 36 and CTX is 208. I believe this shows a stable condition.
I'm now in low bone and out of osteoporosis. While my Dr and I had many discussions re follow up with Reclast and Prolia, I started Prolia yesterday. Was not wild about either but acknowledged that I needed to take one or the other.
I'm 77 yrs, and had never taken any osteoporosis drugs (to the Dr dismay) even though I'd been in osteoporosis for over 10 years. In this case waiting for improved drugs was probably prudent! I've never broken bones, I'm active and in good health. The decisions we have to make are tough but important.

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@annq I have been on Tymlos for 14 months with no side effects. My spine went from -3.1 to -2.4. Congratulations on your results!

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