Hi @kat7707 I absolutely understand where you’re coming from on your thought pattern going forward. Having the loss of your husband so fresh in your mind, this is an awful lot for you to take in. I am so very sorry to hear of your husband’s passing from MDS. While every attempt to treat or cure the disease is made, there is never any guarantees for the outcome. Chemo is very good at wiping out rapidly dividing cancer cells. Unfortunately it can’t discriminate between other rapidly dividing cells, which include blood cells. So the blood counts naturally fall along with the treatment. That left your husband very vulnerable to neutropenia with an infection developing.
So of course you’re very concerned that with pending chemo treatments of your own this could be a similar story for you.

I’m a mentor in this Blood cancer group and also for Bone marrow transplantation, having gone through my own aggressive leukemia journey. While I had great medical teams working with me, I also learned how valuable it is to be able to speak with someone who has walked the walk. There are 800+ discussions in Connect related to Rchop Chemo treatments for lymphoma (and other cancers). I’m posting the results of the search for you. This way you can look through the list to read what’s of interest to you.
Please feel free to tag any member you want to speak with by clicking the blue reply box under their reply. Or type their @name in your reply. That way they’ll get a notification and can respond to you.
Rchop Chemo results:
https://connect.mayoclinic.org/discussion/r-chop-chemo/
Here is one of the discussions you may want to read through:

Anyone had long term remission R-CHOP chemo for Large B-Cell Lymphoma? https://connect.mayoclinic.org/discussion/r-chop-chemo/

Hopefully you’ll be able to get a little more feedback of what to experience in helping to guide you with your decision. If you need a sounding board I’m here for you any time. Will you please let me know what you decide?