Is there a new blood test to determine cause of neuropathy?

Posted by arflmi33 @arflmi33, 2 days ago

Someone just posted on Facebook that their neurologist had ordered "a new blood test from Mayo" that can determine what *caused* their peripheral neuropathy. There was no specific information provided. Does anyone know whether there is actually a new blood test from Mayo that can do this?

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John, Volunteer Mentor | @johnbishop | 2 days ago

Not sure if these are the same but they do sound interesting...

-- Breakthrough Test Enhances Peripheral Neuropathy Care and Research:
https://news.mayocliniclabs.com/2026/03/05/breakthrough-test-enhances-peripheral-neuropathy-care-and-research/
-- Neuropathies - Insights - Mayo Clinic Laboratories - Mayo Clinic Laboratories' new test panel can distinguish among various potential causes of demyelinating neuropathies.
https://news.mayocliniclabs.com/neurology/autoimmune-neurology/neuropathy/

gently | @gently | 2 days ago

arfiml33, your physician can order this test by filling out these forms https://www.testcatalog.org/show/SORD

SusanEllen66 Susan McMichael | @SusanEllen66 | 1 day ago

In reply to @johnbishop "Not sure if these are the same but they do sound interesting... -- Breakthrough Test Enhances..." + (show)

@johnbishop Demyelinating neuropathy is different than your “everyday” version I believe.

My father had CIDP, Chronic Idiopathic Demyelinating P….. (I forget the word). Anyway, he was in terrible pain because the myelin sheath was wearing away off his nerves.

arflmi33 | @arflmi33 | 1 day ago

In reply to @SusanEllen66 "@johnbishop Demyelinating neuropathy is different than your “everyday” version I believe. My father had CIDP, Chronic..." + (show)

@SusanEllen66 I was just at neurology in the past week. They said my neuropathy, currently, is not demyelinating. But they said that they do check for that as it can evolve into that.

arflmi33 | @arflmi33 | 1 day ago

I found this below in a search. There were links in it but the links do not seem to copy over into here. I just search for "is there a new blood test from mayo to find the cause of peripheral neuropathy."

"Yes, Mayo Clinic Laboratories offers advanced tests to identify peripheral neuropathy causes. Recent breakthroughs include a blood test for SORD deficiency, a genetic disorder, and specialized panels that detect autoantibodies linked to immune-mediated or genetic forms of the disease.
These advanced testing options include:
SORD Test: This assay measures levels of sugar alcohols (sorbitol and xylitol) in the blood to quickly diagnose a hereditary peripheral neuropathy.
Autoimmune Neuropathy Panels: These tests identify specific biomarkers that help doctors distinguish between different potential causes, such as axonal or demyelinating neuropathies.
Next-Generation Sequencing (NGS): Genetic panels help establish whether a neuropathy is hereditary rather than acquired.You can read more about these diagnostic options on the Mayo Clinic Laboratories overview page."

jchet | @jchet | 5 hours ago

In reply to @johnbishop "Not sure if these are the same but they do sound interesting... -- Breakthrough Test Enhances..." + (show)

@johnbishop I typed in the https…….website and couldn’t pull up the website for information for my neurologist to send for information. Do you know why?