Discouraged by Prolia & Alendronate side effects

I’m trying to figure out if the fatigue, aches and constipation are related to taking alendronate (bisphenol) or something else - a mild virus??- going on. I am 76yr old in good health other than osteoporosis qI take the alendronate once a week, didn’t have any immediate reactions but wonder if this is a cumulative effect. Probably should discuss with my Dr!

Was on Prolia for about 4 1/2 years; switched to Alendronate due to Prolia side effects. Have been taking Alendronate for about 6 months. I believe it is causing hair loss plus I don't like the realization that this medication stays in my body for "years". Has anyone found natural supplements that help? (aside from Vitamins D, K, and calcium - which I'm taking). Strontium was not recommended by one doctor I talked with. I'm also trying to do bone-building exercises. Would like some advice since I'm aware of Prolia rebound but just do not want to continue medication for the long term if I can help it.

@mbrighton

Have you taken an anabolic medication yet? Those would be Tymlos, forteo or Evenity. Or were you started on bone meds with a bisphosphonate?
Is the alendronate enough to stop Prolia rebound?

@gravity3
I was first put on Risedronate back in 2015 when I was diagnosed with osteoporosis. Then Prolia around 2020 because the Risedronate was not improving my scores. The doctor suggested Alendronate to help prevent rebound from Prolia and many things I read and listened to suggested a bisphosphonate after Prolia. I’m not familiar with the meds you mentioned but can consider them, although I wish I could do away with taking meds altogether.

Hello
How many injections of Prolia have you had? How long have you taken Alendronate?
What you describe is exactly what happened to me.
3 injections of Prolia, multiple infections and autoimmune trigger that left me with Lichen Planus and 50% less hair. Alendronate caused stomach issues, dizziness, and I lost 15 pounds. I stopped after 8 months. Took nothing afterward, had enough
2 years later I had 6 pelvic fractures, doctor admitted they were most likely rebound fractures from the Prolia.
The risk is real. Please explore your options carefully. I know this is a tough journey.
Hugs

Had bad side effects from Prolia, severe fatigue, worse sinus congestion including watery eyes, worsre anxiety, some itchiness. Was hopeful but did not work as I am sensitive to meds where I uaually take half dose which is ok with mt dr. I was told by Dr to not take another shot but increase Vit D and calcim.

@mbrighton

Here is a Mayo article that can be helpful.
https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869