Osimertinib 80 mg

@saurabh - I'm sorry to hear your mother has lung cancer. the brand name for osimertinib is Tagrisso - you can find lots of threads/comments on Mayo Connect about peoples' experiences with it. Tagrisso has been approved for use here in the US since 2016, but there is no generic available here. I've seen references to patients who have taken it for many years. that said, how long it can be used, depends on the type of lung cancer and the overall health of the patient. when osimertinib is used as a second or third line treatment, patients eventually develop resistance. has your mother had biomarker testing of her cancer completed? osimertinib works best on EGFR mutated non small cell lung cancer.

the main side effects are usually: diarrhea, skin rash/very dry skin, weak nails, fatigue. I also had hair loss and an increased heart rate. some people have joint pain.

Hi. I’ve been on Tagrisso since late February for stage 4 adenocarcinoma of the lung. I was dx’d with EGFR L858R Exon 21. There are other variations of EGFR. Without Tagrisso I had a poor prognosis. So I take it every day. I’ve had very few side effects, initially a face rash and cuts on fingers by the nails. If your mom gets a side effect she should check with oncology as there is typically something that can help. I’ve read of people who were on it for years. Personally, I’m very grateful for this medication which has shrunk my tumors! It’s not a cure but a treatment.

Hello @saurabh, I'm glad to read that your mother will start the targeted therapy, Tagrisso/osimertinib. These types of medications have been game-changers in extending the lives of lung cancer patients. I take a different targeted therapy for a different type of mutation (ALK, alectinib, 6 years), and I believe that I wouldn't be here today without these medications. These drugs don't cure the cancer, but they can be very effective for years at a time for the fortunate patients. Were her doctors hopeful? Did they provide answers to your questions? Is she taking the osimertinib along with chemotherapy, or did they stop the chemo? How are YOU doing through this period of diagnosis and early treatment? It's not an easy path.