Long-term stomach problems from being on GLP ones for 3+ years

Yes, some people who have taken GLP-1 medications long term, including Mounjaro and semaglutide-based drugs, do report ongoing stomach problems even after stopping the medication because these drugs intentionally slow stomach emptying and digestion, and in some individuals that effect seems to persist for weeks or occasionally longer, leading to symptoms such as nausea, vomiting, acid reflux, stomach pain, bloating, difficulty eating and feeling full very quickly, sometimes resembling Gastroparesis or severe irritation of the stomach lining, so while it is encouraging that your symptoms are gradually improving after 6 weeks off the medication, many people with similar experiences say recovery can be frustratingly slow and it is definitely worth discussing with your doctor since persistent nausea and poor food intake can sometimes require evaluation for delayed gastric emptying, dehydration, gastritis, reflux damage or gallbladder-related complications.

@jayanthk The potential for these side effects, possibly permanently, is unacceptable to me - I won't take these drugs for this reason. I don't want permanent nausea - it is miserable. Everyone has to decide for themselves if it is worth it. To me, it isn't.

@lylii blindness is another side affect of them ..

I only did 2 injections of semaglutide, quickly experiencing nausea. Even having stopped after the 2nd injection, I'm still experiencing nausea more than 2 weeks later. So even a very short course of the med can cause lasting side effects. I'm hoping that 4-5 weeks from now, this nightmare will be behind me. The only bright side is that I have no desire to overeat, only taking small amounts of food at a time, and drinking plenty of water.