Yes. I was on a few different eye drops to treat Cystoid Macular Edema / Epiretinal Membrane. I was on prednisone, bromfenac and latanoprost drops, and they were not having any effect, so the retina specialist recommended injecting Avastin.
The first Avastin injection went OK without any incident. I didn't feel any difference in the vision, but a week after the injection I had a six month followup appointment with my cataract surgeon and he said my eye pressure in that eye is high at 32. He asked me what happened and I told him about the Avastin injection. He prescribe another eye drops called brimonidine/timolol and wants me to go back in 2 days after using that, and two days later my pressure went back down to 14. He told me to let the retinal specialist know about the high pressure. So a month later at the retinal specialist appointment I told him a month after the injection my eye pressure was at 32. He said that has nothing to do with the injection, but he said we will prove it to you, right now your pressure is 12, and let me inject Avastin again, and we will test your pressure after. So after the injection they waited 5 minutes and an assistant tested my pressure, she jumped up and ran out and yell for the doctor to come into the room and said my pressure was at 59! The doctor immediately told me that he needs to perform an immediate procedure to relieve the high pressure and he basically inserted a needle into my eye to draw out some fluids. The procedure was called Paracentesis. After the procedure the doctor told me to stop using prednisone because he thinks prednisone is the reason my pressure shot up and not the injection.