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← Return to alternative Evenity protocol
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Osteoporosis & Bone Health | Last Active: Jun 25 1:13pm | Replies (6)
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The idea of splitting 12mo Evenity into two separate 6mo courses to capitalize on its anabolic phase during the first 6mo is an interesting approach. The concern is that the bridging agent - Reclast - is a potent antiresorptive with prolonged skeletal retention, which could dampen the effectiveness of the second 6mo Evenity course. Has a shorter-acting bisphosphonate like risedronate, or even raloxifene, been considered as an alternative bridge?
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@mayblin
Thank you for the thoughtful reply. I have the same concern and will speak with my doctor further. Thank you for the suggestions. Perhaps I should have shared additional information. I have taken one dose of Prolia, but am considering the course a new specialist doctor mentioned. He recently further explained that he would monitor bloodwork shortly after beginning Evenity and if there is a rebound effect after Prolia discontinuation, he would move to the Reclast. I am not clear about the odds of a rebound effect after one dose of Prolia. The Evenity would be timed for 6 months after the single Prolia injection.