Prednisone side effects on partner

My Husband was diagnosed with ulcerative colitis about 15 years ago before we got together. It was managed with Sulfasalazine up until a year and half ago he was hospitalized from extreme anemia and needed several blood transfusions. We almost lost him, it was scary. In the last 6 months the doctors decided to change course and get him on a IV infusion to treat his UC. They also put him on a high dose of prednisone. The first corse of infusions didn’t work well unfortunately, so until they could get him on a new higher dose & more frequent treatment with the IV infusions, he’s stayed on the prednisone. Now for 6 months.
I see him but he’s not there. He’s not himself any more. He can be mean, insensitive, quick tempered. He seems to sundown so I know it’s worse at night. So I try to just give him space. He’s put on a lot of water weight and acne I know inside he’s miserable. It’s so hard though! I feel like a monster. It’s so confusing I wouldn’t stay with a person that treats me like this but it’s not his fault. I’m trying to just be patient and leave him alone if he needs. I really just could use some support because I don’t know what I’m doing. It feels so backwards.