Zepbound helpful in managing weight gain on steroid’s?

Posted by livingthelife @livingthelife, 23 hours ago

I have been on Zepbound for the past year and a half. I’ve lost weight and am 15 pounds closer to my weight goal. I am concerned about the weight gain with steroid medication. Wondering how Zepbound will help with all the side effects of weight gain, possible risk associated with varying sugar levels for diabetes etc. Also question increasing my Zepbound dose to off set 15-20 mg prednisone. Thank you. I’m new to PMR.

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

Rheumatolgists are excited about GLP-1 medications not just for weight loss but also for managing inflammatory diseases.
https://rheumatology.org/press-releases/new-research-at-acr-convergence-2025-highlights-potential-of-glp-1-therapies-in-rheumatic-disease-management
--------------------
I would need to look for the video of a presentation at the 2025 ACR conference. At one point in the video a panel of rheumatologists were saying that they should be the ones who prescribe GLP-1 medications. Their reasoning was because they the doctors who prescribe so much prednisone. They feel like they are the ones who should be responsible for their patients who gain weight on prednisone.

REPLY

I used Methylprednisolone (the pills you get for a 6 day dose and ween off of for other quick fix health issues like a bee sting) instead of prednisone for PMR. I started at 20mg on 12/10/24. I ended my meds on 5/20/26. I never gained weight and I didn't change my eating habits. I do enjoy food. I generally eat healthy but I am not one of those skinny people . I could certainly afford to lose 10 lbs even before I started on the meds. I am afraid to take the weight loss drugs since they are quite new.

REPLY
Please sign in or register to post a reply.