Thanks to all for your inputs. I am amazed to hear that some of you can take both without much adverse effect. My wife is definitely off the Ami but tolerates the hydrocodone well although it has only a questionable effect - meaning that it barely dulls the pain to a point where she can sleep. I would think that if we ladder up the scale of narcotics, the next one to try would be the oxycodone (more potent than the hydrocodone?) and beyond that a fentanyl patch. The docs in this corner of Canada won't go all out with the most potent narcotics which I think has everything to do with all the fentanyl BS that Canada was subject to from the White House. It's a shame that thanks to politics, we are being denied the narcotics that are required to relieve our symptoms.