What helps prevent recurrence of endometrial cancer?

I'm sorry to hear this. I've been on Enhertu for 1.5 years though. That's 22 cycles. Results showed NED after 13 cycles. Four is probably not enough.
I have pac/carbo as first line of treatment and after the 6 cycles, my ca 15-3 and 19-9 started to climb. Ca 125 was always relatively low.
I have been taking doxorubicin in pill form for the last three months or so. Don't think it's doing much. Are you getting an infusion of it?

@cookercooker I've been following you since you first began posting here. I'm so glad to know that your current treatment of Enhertu is working for you.

You are so right that cancers are not all alike. The oncologist and cancer care team considers the type and stage of cancer in order to recommend the treatment that will be tailored to you.

Here is my go-to website for the description of types and stages of endometrial cancers. This website has helped me to formulate my questions for my cancer care team.

American Cancer Society: What is Endometrial Cancer?

-- https://www.cancer.org/cancer/types/endometrial-cancer/about/what-is-endometrial-cancer.html

Mayo Clinic: Endometrial Cancer:

-- https://www.mayoclinic.org/diseases-conditions/endometrial-cancer/symptoms-causes/syc-20352461

@colleenyoung
I had a total hysterectomy one week ago stage 1A abnormal P53
Terrified about six rounds of chemo I have a 50-50 chance of it coming back reoccurring

@peghopeful67 I'm adding my welcome to that of @colleenyoung I was diagnosed with endometrial cancer (adenocarcinoma, FIGO Grade 1, Stage 1a) and although this was not considered an aggressive cancer I was terrified by the diagnosis.

With the P53 abnormality it sounds like your oncologist ordered everything possible for you at the time. When will you return for your next check-up (cancer surveillance) appointment? I am hoping that you will be followed closely.

How are you coping with the anxiety you are feeling? You are very welcome here to share as much or as little as you like about how you are feeling. I can assure you that the women here will understand and will provide you with support. Do you see a mental health therapist?

I had FICO 1b endometrial adeno with "extensive LVSI' which meant they were concerned about spread through the lymoh nodes, which often goes to the lungs. So, total hysterectomy then radiation. Now I have a recurrence in the vagina which could have been caught earlier if the person doing my checkups had looked more thoroughly. But still I'd say check-ups are a really important part of prevention, and that can mean using the dilators or whatever to keep the vagina a good size.
And I've lost a lot of weight deliberately, and got fitter than I've even been and only eat sugar in emotional emergencies!

@carointheuk Welcome to Mayo Clinic Connect. From what you wrote it sounds like you’ve adopted a lifestyle change for yourself that is really working. I love your comment that you eat sugar “in emotional emergencies”. As I reflect on how I’ve changed my diet I realize that’s what I do too.

May I ask about the radiation therapy you had? Did you have external pelvic radiation? What is the plan for the recurrence that was recently found?

If only we knew how to prevent recurrence! The theory is healthy lifestyle via diet & exercise, which I try for, but it seems like recurrence is such a crapshoot. And my brain often tells me that if my time is short then I should enjoy the foods that I like. I am almost 4 1/2 years post diagnosis with an 50/50 outlook and 4 years post recurrence with a high grade endometrial cancer. Needless to say, I expect the bomb to drop at any time. My 6 month CT and oncologist visit are coming up, so let the scanxiety begin.

@naturegirl5
Hi, "Yes", I had the full external beam radiation package, the last two weeks of which were gruelling as I was constantly worried about whether I'd manage to have an empty bowel and full bladder at the right time of day. It also left me with a sensitive bowel and constant burping (which I keep under control with organic kefir). The recurrence is not in the usual vaginal spot, the cuff, but 'introitus', right at outer edge where the vagina meets the vulva, right close to the anus. A CT scan, (chest, torso, abdomen) which was not low enough in the abdomen to register the cancer, was NEF for other mets. I don’t have the results of an abdominal MRI yet but a hysteroscopy and excision with Fenton's flap, are booked under a spinal tap, for 19th July with same-day discharge. Because of the proximity to the anus and mild IBS caused by the external beam, both the surgeon and I are trying to avoid brachytherapy which could compromise anal function. But until the histology on the excised material is done, making clear if the cancer has gone through the vaginal wall, no decision can been made.
I would dearly love and feel reassured by, having regular Signatera tests but they're not available on available on the UK NHS and I can't afford £3k a pop. I'm looking round to get adopted by a trial! If I could have the scientific back-up of that test, I'd feel more confident about eschewing brachytherapy this time round.

reoccurrence can happen to anyone regardless of what stage the cancer was diagnosed at and the treatments you received - that is just the way cancer works, it can and typically is totally relentless in it's desire to survive and multply.

the one thing by doctor said and i took to heart was accept all current treatment methods, speak up if something internally doesn't feel right, and always, always, always come to follow-ups/monitoring.

my oncologist is in control of my monitoring (not my gynecologist nor my radiologist). i am currently on a 3 month monitoring schedule. i tell him how my body is feeling, how i'm feeling mentally, and then it's up on the table to have a look on the inside of my vaginal canal. this will continue for 3 years, at which point, it will be monitoring every 6 months for 7 years. once i hit 10 years i will move into a once a year schedule.

the idea behind this consistent monitoring is to catch any cancer growth early. it is easier to treat when the cancer is localized and not systemic.

as far as everything else - i try to eat healthy, i swim every day for exercise, i enjoy my family and friends, i spend spare time doing the things that bring me joy/happiness/peace, and i put everything into the loving hands of God.

@ffr I am in the same boat but 2 and a half years out from last treatment. I lost my original care team due to my insurance. Unable to switch because of my diagnosis and being 72. Do you still have your port?