What do I do after 6 Years of Reclast?

Posted by mangos @mangos, Jun 1 5:31pm

If I start back on Reclast for a 2nd time, this will be a total of 6 years with a drug holiday I had in between, what do I do after that? Im very concerned, as I don’t think I can stay on Recast for longer than 6 years due to the side effects, and the bone building drugs don’t work as well after being on Bisphosphonates so I won’t be able to switch to those, I at a loss of what to do?

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sassysaveur,
good morning.
I'm not sure about Poli, so be sure and respond if I've misunderstood the question or if you have more.
We lose most of the bone we've gain with osteoporosis medications when we quit taking them. So it looks as though we have to continue taking osteoporosis medication in an endless cycle sometimes with short breaks in between them.
Prolia usually creates an intense rebound period when it is stopped, unlike any other medication. You can lose much more bone than you've gained. Reclast has the best record of preventing Prolia rebound. If you've taken one or two shots of Prolia, a person may be safe taking a less intense bisphosphonate than Reclast. The longer a person has taken Prolia the greater number of osteoclast have been stored for release. Reclast is often given for two consecutive years (even without prior Prolia use). Bone markers especially CTX is valuable to determine if a person should continue with a second dose of Reclast.
In the case of Prolia to Reclast. Reclast would be the transition medication, and a person would want to follow up with something else. After the transition drug, you'd no longer be afflicted with the fractures associated with Prolia, but would still be affected by whatever caused osteoporosis, except in the rare cases where you've been able to eliminate the usual cause (steroid use or sometimes hyperparathyroidism and in the younger, than me, nutritional deficiency).
For me it is always a matter of endlessly trying to get back to the drugs that build the best bone, the pth drugs. teriparatide and abaloparatide.
Where are you in the process.
There are people with low T scores who never fracture. We are more likely to fracture these days, because none of us want to slow down

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