Botox for peripheral neuropathy

Hello @jimdandy1 - I haven't heard much discussion on botox injections for treating neuropathy but there is some positive research on the treatment for pain but I don't think it would help with my neuropathy numbness. Here's a 2022 paper on the topic:

--- Use of Botulinum Toxin in the Treatment of Neuropathic Pain: A Case Series (P10-13.009)
https://www.neurology.org/doi/10.1212/WNL.98.18_supplement.864
Have you done any research on the botox injections? How did you learn about the treatment?

Yes I have done a lot of research and was working with a neurologist but insurance will not help with payments because it is not approved by F.D.A and another medical association but I can’t recall the exact name. I called the fda to see what it takes to have this approved and thought maybe there was something that I could do to help with getting it approved but it is way over my head. So I am looking to see if anyone has had this done or know where there is a study that my wife could be a part of.

It's been a year -- have you learned anything new about botox or studies? This was pretty much all I found while browsing, and it's promising but clearly not good enough for the FDA to approve it: https://pubmed.ncbi.nlm.nih.gov/32961514/.

Checking back to ask if anyone has tried botox injections for neuropathy, and if so, did it help? Thank you.

@b54321 this might not be too helpful, but it’s a positive experience I had with Botox. I have small fiber neuropathy and probably another neuromuscular condition. I get tight knots in my muscles that are relieved by dry needling. My medical massage therapist mentioned that my scalp muscles were tight. Who knew that was a thing? I noticed that my forehead felt tight with furrowed brows. I have frequent “tension headaches “ when my neck and shoulders get too tight. So I had cosmetic, not medical, Botox done on my forehead. I felt an immediate release of the tension, and my brow relaxed.
I say cosmetic because I went to an MD owned Aesthetics business and paid out of pocket. I think insurance will pay for a doctor to do the migraine related Botox around the scalp. But I don’t have migraines and don’t have that type of doctor.
It was an experiment on my part, and I can definitely see the possibilities with neuropathy. But I can’t move my forehead or raise my eyebrows after. How could you walk with foot muscles that were paralyzed by Botox? Needs some good research!
I’ve had this done 3 times. But it’s expensive so not in the top of my toolkit.