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ADT or no ADT? What should I ask my Oncolgist?

Prostate Cancer | Last Active: May 28 7:09pm | Replies (50)

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@heavyphil I haven't been able to find it again, but somewhere online there is a brief video of the impact loading exercises, or some of them, that Newton has researched. They all looked completely easy to do. If Boot Camp is a 10, these exercises looked like a 2.

When he gives a talk about this type of exercise, he explains that since he's working with patients who tend to be pretty old, who have advanced disease, and who may not have ever exercised aiming to improve their physical condition up to that point, and he doesn't want to have a study where a significant number of participants suffered grade 3 or higher injury by participating, he is super cautious. He's described not even putting them through the impact loading until he's built them up with a few months of resistance and I think aerobic training.

What I've discovered, not having ever done resistance training aimed at building up muscles before, is that the way to do this has been and is being studied by everyone from body builders to physical therapists to almost anyone you run into in a gym weight room. Newton just researched what effect certain levels of this type of exercise have on various aspects of prostate cancer. He didn't invent the exercises. I suspect impact loading exercise has also been studied by many others for many years, although I haven't looked into it yet. I've only been on Orgovyx for less than 6 months so far so I haven't felt a concern about bone loss.

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Replies to "@heavyphil I haven't been able to find it again, but somewhere online there is a brief..."

@climateguy Impact loading is as easy as running down hill on a hard surface, or down a flight of stairs (make sure not to fall). The combination of gravity and velocity creates quite a force on the legs.

@climateguy
Some studies show that the most loss actually happen in "acute" stage of ADT treatment (initiation of ADT) :
"Men on acute ADT had a similar rate of bone loss to men on chronic ADT. Reversibility in ADT-induced bone loss was observed in those who discontinued ADT. Serum levels of PINP and CTX were higher in acute and chronic ADT users and levels returned to the range of PCa controls when treatment was withdrawn."

I think that it is wise to do all that one can do to prevent bone loss as soon as ADT starts.