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@loribmt
Have you ever heard of having cll/small lymphocytic lymphoma at the same time? Or 2 distinct cell populations? One 28%- cll/sll the other 5% which is unclear.

The doctor said there needs to be more tests. My husband’s flow cytometry identified the flowing-

2 distinct cell populations. The report ended with-

Taken together, these results demonstrate the presence of 2 clonal B cell populations. The immunophenotype of the
predominant population (28% of the total sample) is characteristic of chronic lymphocytic leukemia/small lymphocytic
lymphoma. The significance and relationship of the second smaller population (5%) is unclear (not typical CLL
immunophenotype and different light chain expression). This population may represent non-CLL type MBL or low
level involvement by an unrelated B cell lymphoproliferative disorder. Correlation with clinical and other lab data is
suggested (evaluate for splenomegaly and lymphadenopathy to exclude involvement of other sites.)

I’m not asking for a diagnosis, just wanting to know if you or anyone on here has had 2 distinct cell populations. One of which isn’t evident of what it exactly is.

Thanks in advance.

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Replies to "@loribmt Have you ever heard of having cll/small lymphocytic lymphoma at the same time? Or 2..."

Hi @rimmy2 Yes, it is possible to have CLL and SLL at the same time. I’m away from my computer right now so I can’t do justice to a full search but this is one discussion I recalled with a member who has both diagnoses.

Here are two replies I’d written to @tatayababa who had been diagnosed with both conditions. They contain information that might be helpful for you.
https://connect.mayoclinic.org/comment/813986/
https://connect.mayoclinic.org/comment/815368/
You might find more discussions by typing in CLL + SLL in the search bar at the top.
I’ll be back online tomorrow morning and can help you further. ☺️