My mother had 2 or 3 DES injections in 1959 when pregnant with my younger sister, due to one previous miscarriage. Yes, only one prior miscarriage! Certainly not necessary for that drug intervention! I don't know when in the pregnancy she had them, but they weren't given from any miscarriage symptoms in the pregnancy. She can't remember exactly how many injections, and tried to get her medical records about them, but they weren't available. Probably because too long ago.
My sister had severe PMS, including rage, and weight gain from age 15. She was physically violent with me (not sure if that was only premenstrually), and her psychiatrist put in a mental health facility for a few months in her teen years. She was on the Pill on and off also, which could have made things worse.
She's had precancerous cells on her cervix, and one symptom that isn't being mentioned here, a problem with her son in utero sitting too high in her womb, jammed under her ribs. This resulted in a boney ridge on her son's forehead, and he had surgery on it when he was a baby.
DES can cause a triangle shaped uterus. So her baby didn't have enough room.
I told mum about this, but not my sister (I wasn't speaking to her at the time). Mum said, Don't tell Glenda (sister) due to her temper, as mum was worried Glenda would verbally abuse her and blame her. The whole family knew of her temper and occasional violence. I told Glenda after mum died.
My sister's teen son has anxiety and low self esteem. I can't get along with my sister, as she has like a split personality, nice for awhile, then nasty, critical, and is narcissistic at times. She's 67 now. I haven't heard of any other health problems, but we became estranged again in 2017, after her verbal abuse. Her weight stabilized in her 30s. I think that was after going off the Pill.
I've had to totally cease communicating with her for the final time for my own emotional wellbeing.