Post Evenity DEXA numbers

Posted by susanfalcon52 @susanfalcon52, Jun 7, 2024

So, I have my results after 12 months on Evenity.
Lumbar spine went from-2.5 to -1.8.
Left hip went from-2.0 to -1.8.
For the right hip and right femoral neck,
there are no scores, presumably because they are now titanium.

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Profile picture for mayblin @mayblin

@gravity3, I've got more questions than answers right now, if you don't mind me asking. Between forteo and evenity, which one worked better for you? Also, were you on Fosamax right before starting evenity, and if so, for how long? I'm asking because you mentioned considering a lower dose of reclast after prolia. Are you thinking of the 4mg zolendronate or something even smaller?

I saw in some of your other posts that you might be on bHRT with prolia, are you? If so, do you plan to continue on bHRT alongside reclast, and eventually an anabolic of your choice?

If you are concerned about reclast affecting future anabolic's efficacy, maybe you could wait until bone remodeling suppression eases up - tracking bone markers might guide that timing. Just a thought.

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I was on alendronate for 2 years then forteo for 2 years. Back alendronate
for another 2 years. Evenity for 12 months. Now prolia for one year in
November. I had the greatest gains on evenity. I had much more modest gains
on forteo.

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Profile picture for mayblin @mayblin

@gravity3, I've got more questions than answers right now, if you don't mind me asking. Between forteo and evenity, which one worked better for you? Also, were you on Fosamax right before starting evenity, and if so, for how long? I'm asking because you mentioned considering a lower dose of reclast after prolia. Are you thinking of the 4mg zolendronate or something even smaller?

I saw in some of your other posts that you might be on bHRT with prolia, are you? If so, do you plan to continue on bHRT alongside reclast, and eventually an anabolic of your choice?

If you are concerned about reclast affecting future anabolic's efficacy, maybe you could wait until bone remodeling suppression eases up - tracking bone markers might guide that timing. Just a thought.

Jump to this post

I'm not sure about the reclast amount. I read somewhere that someone had
had 1 mg. But it all seems like a crap shoot. It seems as though most docs
are trying to catch up and we've got to do our research too. Let me know
what you decide and how it goes. I forgot to mention that I started bhrt
last year. So no telling what positive effects this will have on my bone
help.

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Profile picture for gravity3 @gravity3

I'm not sure about the reclast amount. I read somewhere that someone had
had 1 mg. But it all seems like a crap shoot. It seems as though most docs
are trying to catch up and we've got to do our research too. Let me know
what you decide and how it goes. I forgot to mention that I started bhrt
last year. So no telling what positive effects this will have on my bone
help.

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Studies have shown that prior bisphosphonate use can reduce the rebound effect or risk of vertebral fractures after stopping prolia. Your previous 4yr on fosamax probably helps, even though there was a gap year with evenity in between. That said, it might be tough to get your doctor to lower zolendronate less than 4mg after 2 prolia shots, likely due to the lack of data and potential liability concerns, imo. Will you consider fosamax again?

I was asking about your bHRT because I've been using it myself after forteo for its antiresorptive effects, without adding other antiresorptives (bp or prolia). So far so good.

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Profile picture for mayblin @mayblin

Studies have shown that prior bisphosphonate use can reduce the rebound effect or risk of vertebral fractures after stopping prolia. Your previous 4yr on fosamax probably helps, even though there was a gap year with evenity in between. That said, it might be tough to get your doctor to lower zolendronate less than 4mg after 2 prolia shots, likely due to the lack of data and potential liability concerns, imo. Will you consider fosamax again?

I was asking about your bHRT because I've been using it myself after forteo for its antiresorptive effects, without adding other antiresorptives (bp or prolia). So far so good.

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I'll explore using fosamax again. Thank you. Good luck to you. Would love to hear more about your results as you continue on your bone journey.

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Profile picture for susanfalcon52 @susanfalcon52

windyshores,
The endocrinologist and the rheumatologist both said “Evenity.” I had had a sketchy history with Forteo and Tymlos in the past. By sketchy, I mean that I only used each of them for six months. This was because my insurance at that time didn’t cover them. There was a nephrologist here who had made osteoporosis her specialty. She got me six months of Forteo from a drug rep. I had had a dexa at her office and was waiting for someone to call me with results. Finally, the doctor called me - from rehab - to cheerfully say that I had gains. She had fallen at home and broken her neck!
The irony. She told me that when she returned to office in a few weeks, we would figure out how to get more Forteo.
A couple of weeks later, her nurse called me to say that this lovely doctor had died, but had six months of Tymlos in the frig that she had wanted me to have.
I picked it up and used it, but then did nothing for two years. So, I had a lot of bone loss.
If I want to make a grown man cry, I bring up the nephrologist at my visits with the rheumatologist. 🙂
I never had any side effects from either the Forteo or the Tymlos.
Please forgive the long post. Originally, I meant to respond to the question about my numbers not being so bad before Evenity.
The right hip a year ago was
-2.2 and the right femoral neck was -3.2. As I said, those are now titanium, so non-issues.
It seems easier to just replace all of it with titanium. And, cheaper.
Onward to Reclast! I hope my side effect luck has not run out.

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@susanfalcon52 , thank you for sharing. Glad you are doing well now.

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So sorry about your doctor passing.

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