What is the major difference between pregabalin and gabapentin?

Posted by mikead63 @mikead63, Apr 18, 2025

I have idiopathic peripheral neuropathy (diagnosed in January of this year). I was prescribed gabapentin 2-3 hours before bedtime. At this point I am at 600mg which helps while I know it's a low dose for many, at this point it's fine for me. I had not heard of pregabalin until today when I was researching info. in Pharmacy Times. I know that pregabalin is quickly absorbed while gabapentin is absorbed around 3 hours post dose. My question is: IS ANYONE ON PREGABALIN? If so, how is that working out??

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Profile picture for roosterry @roosterry

Hi, I am 84, tried gabapentin over 12 years ago, didn't do much. Switched to gabapentin, and it has been very effective, no problem sleeping at all, and although my feet, particularly the soles are very tender, and feel very hot when walking, I can bear it.. My biggest problem is I also have bone on bone in both knees, and because of heart failure and AFib cannot get an operation. To top it all off, lower arteries in calves are again somewhat clogged, so from the knees down my legs feel like they are made of cement, with pain in calves and hot feet. I would really have a hard time but for the pregabalin. Hope that helps Terry

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Sorry my mistake I switched to PREGABALIN !!!!!!!

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