@moski I had the same experience. One dose and I could not sleep, had to pee every hour, and had legs too weak to walk (even at home), GI problems galore, dizzy, life ending thoughts, and it took weeks to get a bit back to normal.
After 1 day of taking Eliquis.
I stopped my doses after 24 hours, after taking 5mg Eliquis two times that first 24 hours.
5 weeks later and the pain in my joints and musles is so bad that I can not live like this.
Thankfully, my specialist suggested upping my doses of transdermal bio-identical oestrogen to 4 'pumps' (instead of the 3 pumps) to combat the joint/muscle pain.
And that indeed helps.
I am waiting for the full effect of Eliquis to leave my body.
I really do hope it does not take me months to lose all the effects of Eliquis!