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Is there anyone else in the Clinical Trial Sim0500 “Trispecific”
Blood Cancers & Disorders | Last Active: 14 hours ago | Replies (4)Comment receiving replies
Hi Jeff, Since this is a specific clinical trial for patients with relapsed multiple myeloma, it may take a little bit of time before replies trickle in for you.
I did a quick search about the trial and see it’s to evaluate the safety and tolerability, efficacy the drug, SIM0500 in adult with Relapsed or Refractory Multiple Myeloma
You mentioned this clinical trial has been harder than your ASCT and CAR-T experiences. I have a pretty good picture of that in my head from my own experience with a bone marrow transplant so you have my empathy!
What types of symptoms or side effects are you dealing with? Is this an infusion or pill form of medication? Of course, with any clinical trial you won’t actually know if you’re getting the product or not. But if you’re experiencing side effects, that doesn’t seem to be a placebo. Have you had any labs as to how well this is working?
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This is a phase one trial. All patients are given the medication. I had extreme pain the day after the injection. It is a subcutaneous injection. I am assuming this was due the high disease load. I have lost taste for salt and sweet. I had the skin on my hands completely peel off and now my feet . I have had nausea and vomiting such that I have lost 15lbs.
Is it working? Yes definitely. The large mass in neck area almost disappeared overnight and my light chains dropped dramatically. The radiation oncologist said that the lesions that were seen initially and shrunk dramatically. This is all after one injection. I go in for my second injection on Thursday.