Ablation of Non-malignant Pancreatic Cyst

Posted by rmrjr4550 @rmrjr4550, Apr 18 12:34pm

I have a pancreatic main duct IPMN, which has been under surveillance every four months using MRCP scans and EUS/FNA biopsy. Because of age (80) and co-morbidities I am not a good candidate for pancreatic surgery.

Rather than waiting for cancer to develope, I decided to research if there was any proactive approach, and read about ablation using radio or chemo therapy to treat non-malignant pancreatic cysts. Has anyone had experience with this procedure? I understand it is somewhat experimental. If you have, please tell me about your experience. Thanks.

Interested in more discussions like this? Go to the Pancreatic Cancer Support Group.

I'm a 75-yo man who was recently diagnosed with a Branch Duct-IPMN in the tail of the pancreas after an endoscopic ultrasound and a failed biopsy. The cyst is irregular and about 18mm and is composed of four chambers. The pancreatic duct is dilated 5-7mm. Endoscopic doctor recommended a repeat after 6 months. Getting a 2nd opinion from Mayo tomorrow via telephone. Interested in hearing your experiences with dealing with this at an early stage. I have no symptoms; the cyst was found by chance during a CT-scan of my colon due to having an severe attack of constipation, Colon was fine, and I finally had a bowel movement the next day.

REPLY
Profile picture for tikchik1 @tikchik1

I also have been looking into ablation. I am 81 and have multiple cysts in the pancreas - 2 of which are suspicious for malignancy with thickened walls. And, high CA 19-9 and CEA. However, three biopsies have failed to show more than high dysplasia. I am not a candidate for complete pancreatectony. Ablation seems the only proactive option out there. RFA is what is likely. The CHARM trials exclude anyone with suspious neoplasms/characteristics. The procedure doesn't address anything except the cyst fluids according to the doctors I've talked to. I am working with the Hoag Clinic, Dr. Kenneth Chang for a second opinion. They are reviewing my tests to see if partially removal of the suspect cysts is an option and RFA ablation as a secondary procedure if surgery is out. The doctor who was involved with ablations at the Mayo Clinic in AZ where I am staying is currently on indeterminate leave, so CA is the closest recognized facility who is involved with ablation. Good luck.

Jump to this post

@tikchik1 I had Chemablation at Penn State Hospital in Hershey PA yesterday morning. I am only the 2nd person with a main duct IPMN to have this done. The first whose pancreas was dilated to 15mm. I spent the night in the hospital for observation but so far have had no side effects. It’s a short procedure and I may have it redone in 6 months. At 74 this was the only treatment I am comfortable with.

REPLY
Profile picture for jhf99 @jhf99

I'm a 75-yo man who was recently diagnosed with a Branch Duct-IPMN in the tail of the pancreas after an endoscopic ultrasound and a failed biopsy. The cyst is irregular and about 18mm and is composed of four chambers. The pancreatic duct is dilated 5-7mm. Endoscopic doctor recommended a repeat after 6 months. Getting a 2nd opinion from Mayo tomorrow via telephone. Interested in hearing your experiences with dealing with this at an early stage. I have no symptoms; the cyst was found by chance during a CT-scan of my colon due to having an severe attack of constipation, Colon was fine, and I finally had a bowel movement the next day.

Jump to this post

@jhf99 How did your appointment at Mayo go?

REPLY
Profile picture for ltg7622 @ltg7622

@tikchik1 I had Chemablation at Penn State Hospital in Hershey PA yesterday morning. I am only the 2nd person with a main duct IPMN to have this done. The first whose pancreas was dilated to 15mm. I spent the night in the hospital for observation but so far have had no side effects. It’s a short procedure and I may have it redone in 6 months. At 74 this was the only treatment I am comfortable with.

Jump to this post

@ltg7622 I am glad that the procedure is going well for you. What made you comfortable with the chemablation when compared to other treatment options?

REPLY

The only other option was a Total Pancreatectomy and I wasn’t prepared for the challenges afterwards.

REPLY
Profile picture for ltg7622 @ltg7622

The only other option was a Total Pancreatectomy and I wasn’t prepared for the challenges afterwards.

Jump to this post

@ltg7622 I completely understand. Good for you for making an informed decision.

REPLY
Please sign in or register to post a reply.