Reversal of Statin-Induced Peripheral Neuropathy

Posted by jhkenn97 @jhkenn97, Sep 15, 2025

I am curious to know how long intermittent peripheral neuropathic of tingling/burning/sharp or shock-like sensations in extremities and less in torso and face after stopping a statin medication may take to subside? Medication (atorvastatin) was taken for about 16 months and symptoms of neuropathy started about 4 to 6 months ago but have been more pronounced in the past 6 weeks.

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Profile picture for vron @vron

Curious to know if anything ever came from this. Sounds alot like what I've been experiencing for the last year with no answers.

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@vron
No replies from anyone else experiencing this.

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Profile picture for heisenberg34 @heisenberg34

@jhkenn97 How do you know that your statins caused the PN? I haven't heard of any diagnostic tests that can pinpoint the root cause of PN. I will say that it may be coincidental that my own PN started about the time that my Primary put me on it for slightly elevated cholesterol.

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@heisenberg34 Lots of studies support the correlation and it is very convincing. 20 % of the population? That is 1 out of every 5. It comes from excellent sources, not Dr. Oz snake oil. There are other meds available. Please pick an alternative med.

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Profile picture for Suz @db72

Glad you asked this because I had just sent in request to my cardiologist to wean me off the atorvastatin for this reason.

I’ve had severe idiopathic axonal Polyneuropathy for about 20 years that was progressing slowly. Since being put on statins 2years ago my PN has progressed from using a cane to go out to using a wheelchair. My legs feel like they’re incased in lead stockings and my muscles have atrophied to where I’ve taken several bad falls- It’s not particularly painful thankfully, although I’ve been on LDN for years which may make a difference.

I’m hoping I might get at least some amount of healing back because it feels like I’ll eventually become paralyzed. Going off the statin is worth a try.

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@db72 Please switch to any NON-statin, but not Dr. Oz snake oil. There are a host of other excellent meds available from good reputable companies.

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Profile picture for heisenberg34 @heisenberg34

I had lower back and buttocks pain. Pain specialist ran an EMG. Test results indicated neuropathy. This was July 2024. At that point I had no numbness, buzzing, or pain in my legs.It was around that time I was put on statins. Around December I noticed some odd feeling in my feet. A month later there was some in my arms. In early 2025 pain showed up in my feet and back of legs.
So, was it the statins? Who knows?

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@heisenberg34 High probability.

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What are some good, non/statins to help with keeping cholesterol in check?

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Profile picture for madmodulator @madmodulator

@db72 Please switch to any NON-statin, but not Dr. Oz snake oil. There are a host of other excellent meds available from good reputable companies.

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@madmodulator

How about Ezetimibe?

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Profile picture for bigmig @bigmig

@madmodulator

How about Ezetimibe?

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@bigmig I will have my PCP look into it. Thanks for your feedback.

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Profile picture for bigmig @bigmig

@vron
No replies from anyone else experiencing this.

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@bigmig actually, I now wonder if the slight funny feeling in my feet began when I stopped taking statins…it is mild and very intermittent, and feet/toe exercises keep it to low level…

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Profile picture for nycmusic @nycmusic

@bigmig actually, I now wonder if the slight funny feeling in my feet began when I stopped taking statins…it is mild and very intermittent, and feet/toe exercises keep it to low level…

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@nycmusic
How long where you taking statins for?
Why did you stop taking statins?
What did you replace statins with?

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Profile picture for bigmig @bigmig

@nycmusic
How long where you taking statins for?
Why did you stop taking statins?
What did you replace statins with?

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@bigmig long ago, so no detail…but muscle pain was a problem, though not sure how much was due to the statin…it seemed to help some…i didn’t replace statins, just have done the best I could with lifestyle adaptations….i have yet to hear of any great substitute that doesn’t have some issues…we all probably feel the same. Any great info out there, bring it on !

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