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Anyone had immunotherapy for treating soft tissue sarcoma?
I have soft tissue sarcoma cancer in my left thigh. Competed radiation therapy, now scheduled for surgery. The oncologist said my age limits my ability for chemotherapy, the surgeon said there is evidence of for good recovery result from immunotherapy. The oncologist first said is an avenue for treatment and said perhaps not, because she believes I have an autoimmune deficiency, because of the Colitis disease I had and was treated via surgery over a decade ago. The colorectal surgeon said no, the intestines were removed and no autoimmune disease exists from that ailment. Has anyone had experience with using the immunotherapy for treating sarcoma cancer?
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It took 16 months and 6 doctors to diagnose my Epithelioid Angiosarcoma-started in the head. It’s a cancer of the lining of the blood vessels. Since being diagnosed I’m on the 4th. Chemo type, and it’s been one and a half years of treatments, including immunotherapy. I did do Immunotherapy (Keytruda) for 3 months, but it unfortunately did nothing for me and was not slowing the progression. Everyone responds differently, and there are so many types of sarcomas.
Prayers for you in your journey that your oncologist finds the best treatment that works for you.
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1 ReactionTotally agree with you ctflyr
What a negative and incorrect comment!!
Hello
I didn't express myself clearly enough.
I am diagnosed with classical HIV negative Kaposi sarcoma with lesions only on the skin of the foot, meaning there are some colored spots on the sole of the foot and on the toes. I don't know if I can post photos here. There is no other organ affected, but I would like to know more about immune treatment or other treatment. At the moment I am only taking 3 months in the summer.
I wrote it wrong. At the moment I only take 3 months in the spring and 3 months in the fall.
I had a large chondro sarcoma removed from my pelvis 10 years ago. A further tumour in the same place was removed 3 months ago
My son was diagnosed with epithelioid sarcoma in August 2025. The primary tumor was located in his foot, and he had two metastatic lesions in his leg. He completed six cycles of chemotherapy, which reduced the primary tumor by 60% and led to the disappearance of the metastatic lesions.
Given this positive response, the medical team has proposed performing an isolated limb perfusion procedure. This is an extracorporeal technique in which high-dose chemotherapy is delivered directly to the affected limb in order to eliminate or significantly reduce the primary tumor, while minimizing systemic exposure.
At the same time, he will begin treatment with Tazemetostat, a targeted therapy specifically approved for epithelioid sarcoma, which is manufactured in the United States.
It seems that you’ve been going through this for a longer time — I truly hope everything is going well.
Sending you my best regards.
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3 ReactionsHe also received doxorubicin as part of his treatment.
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I had my 5th treatment yesterday of doxorubicin and Keytruda. Last summer, I had radiation and surgery to remove the myxofibrosarcoma on my hip. They thought it was removed encapsulated with clear margins. However, it showed up again in my lungs at the 3 month check. With the current treatments, most of the tumors in the lungs have shown some shrinkage while one tumor grew slightly since the last scan. I feel better and can breathe easier. Hope this helps.
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3 ReactionsYour experience is very similar to mine with similar results.
@quichewithmayo
Hi there. I was diagnosed with stage 3 indifferentiated pleomorphic sarcoma. Have had consults at UCDavis, UCSF (Dr. Monga & Dr. Murray - surgeon). Last consult scheduled at Stanford next week. Before we knew the exact type, both institutions recommended 5 weeks radiation, 1 month to heal, followed by surgery. Following further pathology, Dr. Monga now recommends immunotherapy for 1 year. I am close to your age - 69. Was the only side effect you had diarrhea, as I can handle that. It’s the risks to thyroid etc etc that concerns me. Any thoughts?