P1NP number on Tymlos
After 3 months on Tymlos, my P1NP bone marker has increased by 50% to 109. I was initially excited, but am wondering if this is excessive. Anyone else had numbers like this?
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
Connect

@yogagirl57, were you on an antiresorptive before Tymlos.
@gently No I wasn’t on anything before.
@kfhoz thank you. Look forward to watching.
-
Like -
Helpful -
Hug
1 Reaction@yogagirl57
CTX rises on Tymlos, your rate is surprising. Before worry, though, consider lab or transcription error. CTX has risen as high as 49% in studies where exercise is performed prior to the test. And CTX levels change throughout the day.
What was your increase in P1NP.
Lastly, fracture can increase CTX by 69%, but don't even think about that, unless you have new pain, until you repeat the CTX marker.
I can never wait for the next doctor appointment and frequent Jason Health https://www.jasonhealth.com/
qt17406 Collagen Type I C-Telopeptide (CTx) $50.00
Lab Collection Fee $18.00
Grand Total $68.00
Your doctor has a full view of your medical situation and isn't concerned, which should be relaxing, but can put a person on greater alert. She is prescribing the best medication and so deserves trust.
I don't even have a basic medical background and am hoping you went to the gym before your draw.
,
@gently I can’t remember now if I went to the gym prior, and had no idea that I shouldn’t exercise prior to the test. I am very active and do cardio and weights alternating days so I’m sure that I did one or the other; but it would have been the day prior since I had the blood test early in the morning. How long should you hold off exercising prior to the test? I guess I’ll have to wait for the results for the next test in 3 months. I just thought that increase was crazy ; but, again. , my Endo seemed very unconcerned. I do not have a baseline on P1NP . That was the first time I had been tested.
yogagirl157, Unrelated studies indicate that the usually persists for 4 hours. Test before morning exercise, but not before 8am. Weights and cardio are know to raise CTX. That's a relief.