Possible failure of Nissen Fundoplication (2021)

Posted by ufoundme @ufoundme, Dec 28, 2025

I had a Nissen Fundoplication in July 2021 due to hiatal hernia, severe gerd, etc. I had major complications in September 2021 prompting the the surgeon to redo the surgery but adding an "anchor" from the stomach to my abdomen. I've had mild gerd but it has been manageable by meds for 4 years. Recently I got really sick (nausea & vomiting) and since then have had intractible nausea accompanied by frequent deep burping. I'm having an endoscopy next week but am very concerned the Fundoplication has failed again. Has anyone experienced something similar and what was the outcome?
53/F.

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Yes I was admitted to hospital last week with dehydration as could not keep anything down. I had a endoscopy done they said the Nissan Fundaplication was looking and they did not have the answers as to why I am
Having these issues. They did say I was showing quite abit of inflammation inside when they put the scope down so I am not if that’s causing the problem?
But I still can’t really eat and stil have quite bad pain in back and abdomen area. So Iam at a loss as to want it is . I am now home from hospital. They suggested trying omprazole for 6 weeks

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I had the Nissen Fundoplication done 1 year ago for Hiatal Hernia and reflux (daily). Since then, I have had shortness of breath that won't go away. I've been scoped for vocal cord dysfunction, and the vocal cords are in good shape.
Has anyone else with the NF experienced shortness of breath?

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I should have followed up to my original post sooner. My Endoscopy was normal and my Fundoplication is still intact. Shortly after the endoscopy, I started getting really sick with severe nausea and a whole bunch of other symptoms. My GI ran a myriad of tests which only made me sicker, i had to wait 3 weeks for a gastric emptying study which finally confirmed my diagnosis was Gastroparesis.
I've had to change all my meds, my diet, my lifestyle, and my work schedule. I can't even leave the house for more than a couple hours at a time. I wouldn't wish this on anyone. Sorry for the long post!!

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I just had an endoscopy and it confirmed my suspicions that my Nissen wrap surgery was unsuccessful. The wrap only lasted a short few months and then all my acid reflux symptoms were back. I believe I had the surgery two years ago. Now I have been told to continue taking two anti-acids a day so back to square one. The surgery was a waste of time and money!

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Hi @jlharsh
Things are no better and I just can’t seem to get on top
Of the pain which is in the side of stomach and now wondering if it’s a bowel issue? I still can’t eat properly at all so I am not sure what is going on.

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Profile picture for lillymo1 @lillymo1

I just had an endoscopy and it confirmed my suspicions that my Nissen wrap surgery was unsuccessful. The wrap only lasted a short few months and then all my acid reflux symptoms were back. I believe I had the surgery two years ago. Now I have been told to continue taking two anti-acids a day so back to square one. The surgery was a waste of time and money!

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@lillymo1

Do you take anything like Prilosec?

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They have given me the omeprasole to use for 6 weeks twice a day to see if makes any difference

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Profile picture for bajjerfan @bajjerfan

@lillymo1

Do you take anything like Prilosec?

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@bajjerfan

I take two Prevacid daily. The pills only keep the burn down but does not prevent acid reflux. I was told I have an ulcer in my esophagus. I have read that these pills are not good to take long term. Once you start you cannot stop.

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Profile picture for traceskippy @traceskippy

Hi @jlharsh
Things are no better and I just can’t seem to get on top
Of the pain which is in the side of stomach and now wondering if it’s a bowel issue? I still can’t eat properly at all so I am not sure what is going on.

Jump to this post

@traceskippy I read your earlier that your doctor is recommending omprazole after a scope confirmed your Nissan Fundoplication looks good but also identified inflammation and dehydration. You are making progress working with your doctor. Still, I imagine it feels like answers are not coming soon enough.

It may help to see how others are eating following digestive problems and surgeries. You may pick up some tricks to try as you continue learning more about what is happening.
- Connect Discussion: How Do I eat After Digest Tract Surgery?
https://connect.mayoclinic.org/discussion/how-do-i-eat-after-digestive-tract-surgery/
Here is Mayo Clinic overview of the medication you are considering:
- Omeprazole Summary
https://www.mayoclinic.org/drugs-supplements/omeprazole-oral-route/description/drg-20066836
Do you mind sharing more about your pain and what happens when you eat, what you eat? Do you plan to try omprazole (proton pump inhibitor)?

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