I just lost 8% of my bone from using omeprazole to control my reflux a

Posted by naoshapiro1 @naoshapiro1, Apr 11 9:05am

After an esophagectomy I have used omeprazole for two years and lost 8% of my bone so I'm thinking about using rec clast ---an infusion. What are some of the pluses and minuses?

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Profile picture for lightlifts @lightlifts

My case is not as severe as yours. I do have a hiatal hernia and GERD for years. I am supposed to be on Prevacid twice a day but limit it to once a day due to bone loss.
I have been struggling with taking Tymlos for 7 months, it makes me very fatigued and causes extreme belly bloat which is a killer for my self confidence. So far I don’t even know if it’s working. I started on half the dose to limit the side effects but my blood scores weren’t showing improvement so now I am up to 7 clicks back to in the abdomen again for better absorption but may go back to thighs due to belly bloat. I also have Hashimoto’s thyroiditis and many back issues. I do exercise everyday do small group personal training twice a week with weights and generally suffer from soreness other areas due to that. I also walk, do pool water aerobics and bicycle. So far nothing is helping with weight loss, but at least I know I’m doing what I can. I Understand your comment about wanting to throw in the towel. Sorry I can’t offer much advice but encourage you to stay the course and commend you for all you are doing . It is very hard. My hat is off to you!

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@lightlifts i'm so sorry. I hope you have a good endocrinologist and a good gastroenterologist many things going on with you. I'm so sorry eating some small meals very important staying elevated when you go to sleep drinking tenderness of water in between making sure that you don't before you go to sleep sticking with organic when processed foods may be trying to be a vegan. I'm so sorry for your pain discomfort.

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Profile picture for gently @gently

naoshapirol, just a few thoughts. omeprazole it thought to induce bone loss by thwarting the absorption of calcium. Reclast prevents the loss of bone which limits your body's access to ready calcium. Combined the two medications could increase hypocalcemia.

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@gently Confirming your note omeprazole, and adding that better results happen with Calcium Citrate supplements when you are on a PPI.

Example reference:
https://www.health.harvard.edu/newsletter_article/calcium-curious
"People taking medications that reduce stomach acid — such as the proton-pump inhibitors (Prevacid, Prilosec) or the H2 blockers (Tagamet, Zantac) — should take a CALCIUM CITRATE supplement because lower amounts of stomach acid mean they won't absorb calcium carbonate properly."

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Profile picture for naoshapiro1 @naoshapiro1

Thank you for the information about the longer infusion time. My T scores were -3.7 I think and I was told I lost about 8% of my bone in 2 1/2 years. It's probably due to the omeprazole which I have to take because of terrible reflux because of my esophagectomy and gastroparesis Fotteo is not recommended for people who have had cancer because it could cause bone cancer I had radiation and chemo and then had my esophagus removed in June 2019. I'm not willing to take the chance that I could get bone cancer. I don't want to die what I'm going to do is take the infusion and then go to a physical therapist and get physical therapy to gain bone lifting weights safely under supervision because I always tend to overdo everything and even though I do 40 minutes of exercise with bands every morning for the past six years, and walk over two hours a dayit's apparently not enough to counteract the omeprazole. And Pepcid,. I also work with a nephrologist because I make kidney stones so I have to drink 10 glasses of water a day between walking for exercise and drinking all that water and eating four small meals a day and taking extra calcium due to my 24 hour urine test results I'm on a very very rigid schedule. It's all I can do to keep happy with teaching cello, maintaining my connections being a loving partner and trying to do regular things like book clubs, etc. sometimes I think I'm in way over my head.

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@naoshapiro1

Do you have hypercalciuria or hypercalcemia? If you have the former, adding calcium may not help, but rather might make those kidney stones worse.

My rheumatologist gave me a primer about taking in too much calcium - we generally get about half of the RDA (1300 mgs) in our everyday food intake and only need to supplement with another 650 mg.

We are told “the more calcium, the better” which may in fact be causing more harm than good. Some of us have systems that process calcium differently and we are feeding the OP monster by overdoing it. There is only so much calcium we can utilize.

I have hypercalciuria and currently take chlorthalidone to tell my body to direct the available calcium back to my bones, rather than literally peeing that valuable and bone-sustaining mineral down the drain.

Take heart, OP is not a death sentence, but the complications can be devastating. Talk to your doc and remember we’re all in this leaking boat together patching holes and bailing water!

Happy Masters Tournament Sunday. Cheers!

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Profile picture for beanieone @beanieone

@naoshapiro1

Do you have hypercalciuria or hypercalcemia? If you have the former, adding calcium may not help, but rather might make those kidney stones worse.

My rheumatologist gave me a primer about taking in too much calcium - we generally get about half of the RDA (1300 mgs) in our everyday food intake and only need to supplement with another 650 mg.

We are told “the more calcium, the better” which may in fact be causing more harm than good. Some of us have systems that process calcium differently and we are feeding the OP monster by overdoing it. There is only so much calcium we can utilize.

I have hypercalciuria and currently take chlorthalidone to tell my body to direct the available calcium back to my bones, rather than literally peeing that valuable and bone-sustaining mineral down the drain.

Take heart, OP is not a death sentence, but the complications can be devastating. Talk to your doc and remember we’re all in this leaking boat together patching holes and bailing water!

Happy Masters Tournament Sunday. Cheers!

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@beanieone I don't have either of those conditions and it's all very very very complicated and I'm very very grateful for your response

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Profile picture for kfhoz @kfhoz

@gently Confirming your note omeprazole, and adding that better results happen with Calcium Citrate supplements when you are on a PPI.

Example reference:
https://www.health.harvard.edu/newsletter_article/calcium-curious
"People taking medications that reduce stomach acid — such as the proton-pump inhibitors (Prevacid, Prilosec) or the H2 blockers (Tagamet, Zantac) — should take a CALCIUM CITRATE supplement because lower amounts of stomach acid mean they won't absorb calcium carbonate properly."

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@kfhoz I have a urologist and endocrinologist and nephrologist, and I am taking extra calcium citrate with every meal. I'm being watched very carefully thank you so much.

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Profile picture for naoshapiro1 @naoshapiro1

Thank you for the information about the longer infusion time. My T scores were -3.7 I think and I was told I lost about 8% of my bone in 2 1/2 years. It's probably due to the omeprazole which I have to take because of terrible reflux because of my esophagectomy and gastroparesis Fotteo is not recommended for people who have had cancer because it could cause bone cancer I had radiation and chemo and then had my esophagus removed in June 2019. I'm not willing to take the chance that I could get bone cancer. I don't want to die what I'm going to do is take the infusion and then go to a physical therapist and get physical therapy to gain bone lifting weights safely under supervision because I always tend to overdo everything and even though I do 40 minutes of exercise with bands every morning for the past six years, and walk over two hours a dayit's apparently not enough to counteract the omeprazole. And Pepcid,. I also work with a nephrologist because I make kidney stones so I have to drink 10 glasses of water a day between walking for exercise and drinking all that water and eating four small meals a day and taking extra calcium due to my 24 hour urine test results I'm on a very very rigid schedule. It's all I can do to keep happy with teaching cello, maintaining my connections being a loving partner and trying to do regular things like book clubs, etc. sometimes I think I'm in way over my head.

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@naoshapiro1 Hi! I play the cello too but no longer teach due to Dupuytren's disease in my hands. It is a daily battle isn't it? To just keep going and doing the things we love. I also have reflux and did not know that omeprazole could reduce my bone density. You mentioned Pepcid, is that a good alternative? I have been trying for over a year without any luck to find a bone drug that I can tolerate.

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Profile picture for musiclvr @llander1966

@naoshapiro1 Hi! I play the cello too but no longer teach due to Dupuytren's disease in my hands. It is a daily battle isn't it? To just keep going and doing the things we love. I also have reflux and did not know that omeprazole could reduce my bone density. You mentioned Pepcid, is that a good alternative? I have been trying for over a year without any luck to find a bone drug that I can tolerate.

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@llander1966 I take omeprazole 40 mg at 4:15 AM and it's 7 PM and I take Pepcid 20 mg one at 11 AM and two at 8 PM because I had an esophagectomy and I have terrible reflux as a result. I also have gastroparesis I am 99% vegan organic and my last meal is at 4:30 which is just one and a half pieces of sourdough bread and about 5 g of olive oil and 1 tablespoon of nut butter, which I make out of several kinds of nuts. I can't take a bone builder because they all have bad side effects, but I might be able to take rec last as an infusion. But apparently there are side effects that could be very very bad. It is recommended that you take this medicine in a one hour infusion not a 15 minute infusion which most doctors do so I'm in the process of working on that. I took Fosomax and actonel decades ago, but because of my esophagectomy, I can't do that now I lost 8% of my bone in 2 1/2 years so I have to start lifting weights even though I do exercise every morning with bands and I walk two hours plus every day, but it's not working because the Omeprazole is taking bone away from me. I have a nephrologist or urologist and endocrinologist a primary a lung specialist because I had aspirational pneumonia last July. There's a Doctor Who deals with bone diseases in Stamford California. His name is Dr. David KARPF I'm gonna try to call him and see if he can send the pro protocol force taking the infusion of RECLAST this is all the information I can give you. I have a zoom right now. You can always write to me naomi shapiro good luck. Good luck good luck.

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This comment is not for those who must take a PPI for their medical conditions. I was put on a PPI after my doctor incorrectly diagnosed me with Barrett's esophagus. After taking it for a few years, my DEXA scores got a lot worse. I very slowly weaned myself the PPI and replaced it with Famotidine twice a day. Famotidine is not significantly associated with bone loss, unlike proton pump inhibitors (PPIs), which have been linked to lower bone mineral density. Therefore, famotidine is generally considered more bone-friendly compared to other acid suppressants.

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Profile picture for daisy17 @daisy17

This comment is not for those who must take a PPI for their medical conditions. I was put on a PPI after my doctor incorrectly diagnosed me with Barrett's esophagus. After taking it for a few years, my DEXA scores got a lot worse. I very slowly weaned myself the PPI and replaced it with Famotidine twice a day. Famotidine is not significantly associated with bone loss, unlike proton pump inhibitors (PPIs), which have been linked to lower bone mineral density. Therefore, famotidine is generally considered more bone-friendly compared to other acid suppressants.

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@daisy17 the problem is that I was having such bad reflux that was lasting an hour that I went on omeprazole which took away. I've only had one bad incident of reflux last week since July of last year. The reflux is very frightening because I've had an esophagectomy and I have burning in my throat for one hour and I use throat cold tea and Pepcid and Tums. It's frightening and I actually had aspirational pneumonia from that reflux so I'm really afraid to go off the omeprazole. I don't know what to do.

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Profile picture for naoshapiro1 @naoshapiro1

@lightlifts i'm so sorry. I hope you have a good endocrinologist and a good gastroenterologist many things going on with you. I'm so sorry eating some small meals very important staying elevated when you go to sleep drinking tenderness of water in between making sure that you don't before you go to sleep sticking with organic when processed foods may be trying to be a vegan. I'm so sorry for your pain discomfort.

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@naoshapiro1
Thank you so much for your thoughtful reply, I appreciate it.

I think if I were you I would likely stay on the omeprazole.

There is something else which I have not tried and it may or may not be helpful in your case. It is called reflux raft.
http://www.refluxraft.com if you want to check it out.

Let us know how you make out with your research on Reclast. I will keep you in my thoughts.

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