@jules725 I’m not sure what your dosage for Crestor is, but I have had to start taking it again and have been able to do so for 11 months without issue. It has greatly lowered my cholesterol again and I am only taking 5 mg. I am, however, also taking .5 mg of Xanax every morning. A much better situation than I was in before, but still lack energy and motivation frequently. I hope you show improvement soon. Maybe it’s just a period of adjustment?? The problem I spoke of in my first post caused a 35 pound weight loss and what felt like a complete breakdown. I slowly pulled out of it when I was taking no medication, but the doctor said that was not sustainable when he saw my numbers jump back up after just six months. I never did return to beta blockers though.