Dr recommending fosamax after serious wrist fracture .

Posted by bridget11 @bridget11, Apr 5 10:25pm

64 yr old female with recent t-score of -1.8 (have actually been at that number for 6 years) I fell really hard while running down hill relatively fast and broke my wrist on Feb 13. 2 plates and 14 screws later I am still recovering. The surgeon indicated my bone was soft and he felt if was a fragility fracture.. I guess because of what it looked like and how bad it was. So my PCP thinks I should start Fosamax now. I prefer to focus more on heavy strength training and plyos which I have been doing but can do more. Should I find a doctor that is more experienced in this area to help me navigate this issue? I am also small - 5'2" 97 lbs so my bones are small. Thanks for any input on this.

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Profile picture for oopsiedaisy @oopsiedaisy

@bridget11 There are underlying diseases that can make your bones soft. Someone here recently was diagnosed with hypophosphatasia (HPP). This is a genetic disease which is confirmed using genetic testing. I’m mentioning it because of your surgeon’s comment on your bones being soft. Bisphosphonates like Fosamax are contraindicated for people with HPP and can make the disease worse.

This is why it’s important to see a well-informed endocrinologist. I started seeing one last year and found out that I have a condition which worsens osteoporosis (idiopathic hypercalciuria). No one ever did full testing on me before her and I’ve had osteopenia/porosis for 12 years.

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@oopsiedaisy Thank you! I am looking for one in my area before I do anything else.

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I took ONE FLOSAMAX PILL FALL '25. IM STILL DEALING WITH WALKING ISSUES AND STILL SM PAIN GOING UP STEPS. RUN FROM THAT STUFF! READ ABOUT THE LAWSUITS. MERK, THE DRUG CO HAS BEEN SUED IN CLASS ACTION SUITS.

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Profile picture for llc52infofo @llc52infofo

I took ONE FLOSAMAX PILL FALL '25. IM STILL DEALING WITH WALKING ISSUES AND STILL SM PAIN GOING UP STEPS. RUN FROM THAT STUFF! READ ABOUT THE LAWSUITS. MERK, THE DRUG CO HAS BEEN SUED IN CLASS ACTION SUITS.

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@llc52infofo Stop. Your problems have nothing to do with taking a single pill.

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Profile picture for cat1203 @cat1203

A good pretty comprehensive overview of the history of osteoporosis treatment and the various drugs. https://medshadow.org/conditions-treatments/osteopenia-osteoporosis/osteoporosis-treatment-screening-medications/

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@cat1203 Thanks! This is really good. It seems maybe I would qualify for the anabolic meds (not that I want to) if they call my fracture a fragility fracture. Not sure who decides that - I fell super hard running downhill. This is why I need a specialist to look at my case.

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Profile picture for daisy17 @daisy17

Your DEXA score is not even within the osteoporosis starting point of -2.5. My scores are much worse than that (-2.7 at hips and -4.1 in spine) and I have refused any bone meds thus far (no fractures to date).

Like you, my doctor recommended Fosamax (I can't take Tymlos or Forteo due to parathyroid issues). I have decided not to take it based on articles I read that said it offers minimal fracture prevention benefits in postmenopausal women without a prior fracture or vertebral compression. It does make your DEXA numbers better because you retain old bone. The only reason I'd consider a bone drug was if it offered considerable fracture prevention, because isn't that the reason for taking a medication?

There are many articles about studies done on this, here is one: https://www.amjmed.com/article/S0002-9343(24)00101-3/fulltext
The last paragraph offers a summary of findings: "for patients with osteoporosis based on bone density alone, treatment benefits are less certain. Hip fracture risk reduction is modest and not supported in patients without a history of fracture. Reductions in vertebral fractures are substantial regardless of baseline risk, but whether these reductions correspond to less chronic pain and disability is unclear. Clinical evidence is weaker for newer agents. Future guidelines and reviews on osteoporosis treatment should clearly distinguish between primary and secondary prevention of fractures to best inform clinical decision-making. Despite guideline recommendations and calls for more screening and treatment, there are legitimate reasons for some clinicians and patients to opt out."

Another article by Consumer Reports: https://www.consumerreports.org/cro/2012/04/popular-osteoporosis-drugs-come-with-mounting-concerns/index.htm
From this article: "Bottom line. Bisphosphonates offer only modest benefits in building bone and preventing fractures, and that should be considered along with the risks."

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@daisy17 Thanks for this helpful info. Yes I am confused because my scores are not that bad. Its the serious fracture that seems to be the issue so I need to have a specialist did into this more before I even think about taking meds. I'm just anxious to get back in the gym one this study wrist is more functional! For now I am going to work on the plyos at least.

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Profile picture for njx58 @njx58

@llc52infofo Stop. Your problems have nothing to do with taking a single pill.

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@njx58 Please don't make dismissive comments. No one can predict whether someone may experience side effects from taking just one dose of a medication.

I found these comments on AI Assist: "Yes, one dose of Fosamax (alendronate) can cause side effects, including abdominal pain and gastrointestinal issues. While side effects may vary, some individuals may experience discomfort shortly after taking the medication."
And: "Yes, taking Fosamax (alendronate) can cause pain as a side effect, including bone, muscle, or joint pain. This pain can occur shortly after starting the medication and may vary in severity."

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Profile picture for bridget11 @bridget11

@cat1203 Thanks! This is really good. It seems maybe I would qualify for the anabolic meds (not that I want to) if they call my fracture a fragility fracture. Not sure who decides that - I fell super hard running downhill. This is why I need a specialist to look at my case.

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@bridget11 something I've always wondered about - seems like there is no difference between a fragility fracture and a traumatic fracture as far as osteoporosis goes. I do not believe I broke my wrist because my bones were too frail to survive a car wreck involving an air bag smacking my wrist and breaking it. And that was the opinion of the EMT and the ER doc... that people break their wrists commonly in wrecks; not just we little old ladies! But like trying to achieve the baseline DEXA of a 30-year-old woman just another piece of confusion in regard to osteo.

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Profile picture for llc52infofo @llc52infofo

I took ONE FLOSAMAX PILL FALL '25. IM STILL DEALING WITH WALKING ISSUES AND STILL SM PAIN GOING UP STEPS. RUN FROM THAT STUFF! READ ABOUT THE LAWSUITS. MERK, THE DRUG CO HAS BEEN SUED IN CLASS ACTION SUITS.

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@llc52infofo

I took fosomax for 5 years. No noticeable side effects. It was effective. I don't believe it is useful to tell others what to do or not do. We are individuals and our bodies respond individually. What is useful to me is hearing about other people's direct experience.

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Yes I agree. It is good to hear other's experiences and attached research and other good source of data has been very helpful. We all make our own decisions based on our unique issues and background. I just don't like to take any meds if I don't have to but if there is one that is helpful I am not opposed. Right now, I would do almost anything to avoid going through with very difficult wrist fracture!

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Profile picture for jozer @jozer

@bridget11 something I've always wondered about - seems like there is no difference between a fragility fracture and a traumatic fracture as far as osteoporosis goes. I do not believe I broke my wrist because my bones were too frail to survive a car wreck involving an air bag smacking my wrist and breaking it. And that was the opinion of the EMT and the ER doc... that people break their wrists commonly in wrecks; not just we little old ladies! But like trying to achieve the baseline DEXA of a 30-year-old woman just another piece of confusion in regard to osteo.

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@jozer I know!!! That makes no sense. I am not frail ....lol. I run marathons and I regularly finish in the top 5 in my age group in major marathons like NYC, Chicago, and Boston. I do squats and other exercises with 50-80 lb weights and was working up to higher until I had this set back. But I am small and have small bones but have been like that my whole life. I am getting an appointment with an endo so I'll update after that.

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