Studies on Covid 19 vaccine causing PMR

Posted by bruce7501 @bruce7501, Mar 30 10:12am

Anyone familiar with ongoing studies on the COVID-19 vaccine as a possible cause of PMR?
I understand there are such studies.
Since one possible cause of PMR is believed to be a viral infection, could you trigger one by getting a vaccination? The many vaccine skeptics certainly warned us about possibilities like this.

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

Profile picture for kare1 @kare1

Wasn’t PMR a thing way way before Covid vaccines?

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@kare1
No one knows the cause of PMR. Viruses are suspected of being capable of triggering an immune response that can cause other disorders. Our immune system needs a trigger before it can short circuit and work against us. Maybe the trigger for PMR is a virus, maybe it's a vaccine, maybe it's traumatic stress or maybe it's the way our immune system ages. No one knows. Our symptoms and pain levels vary from person to person, so why should we expect the same cause?

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Profile picture for kare1 @kare1

@pmrnew
-that hair falling out is a real bummer. Add the fragile skin damage from pred sure adds to looking very OLD! All I have to do is glare at my arm & that blood blister thing appears. What the heck. And the weight gain. Oy vey. I’m curious when does the pred weight gain begin to lessen? Do we have to be totally off prednisone to see some of that tummy (etc!!) fat go away?? Anyone experienced weight loss after prednisone?

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@kare1 I can relate.

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Profile picture for kjoed53 @kjoed53

@kare1
No one knows the cause of PMR. Viruses are suspected of being capable of triggering an immune response that can cause other disorders. Our immune system needs a trigger before it can short circuit and work against us. Maybe the trigger for PMR is a virus, maybe it's a vaccine, maybe it's traumatic stress or maybe it's the way our immune system ages. No one knows. Our symptoms and pain levels vary from person to person, so why should we expect the same cause?

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@kjoed53
As you posted this I’m reflecting over these last few years. I retired in 2019, watch Covid ravage our world & in 2022 left the south 😞 to move closer to daughter in the Midwest 🙄. Then in spring/summer of 2023 got sick w/2 stomach viruses & 2 bouts of diarrhea all w/in 6 mo!! I’ve never been sick like that. EVER. Was always proudly healthy! Folks here said it was new grandbaby bringing me new germs from her play time at the Y. (I worked at a library before retirement & never ever got sick (maybe a cold every 4/5 yrs? there are PLENTY of germs in the public library.) Anyway things calmed down in 2024 till end of that year when PMR struck.
Maybe stress of a move by myself to a really new area at the tender age 69/70? & new germs? The vaccines?
You’re right who knows.
Just face forward.

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Profile picture for kare1 @kare1

@kjoed53
As you posted this I’m reflecting over these last few years. I retired in 2019, watch Covid ravage our world & in 2022 left the south 😞 to move closer to daughter in the Midwest 🙄. Then in spring/summer of 2023 got sick w/2 stomach viruses & 2 bouts of diarrhea all w/in 6 mo!! I’ve never been sick like that. EVER. Was always proudly healthy! Folks here said it was new grandbaby bringing me new germs from her play time at the Y. (I worked at a library before retirement & never ever got sick (maybe a cold every 4/5 yrs? there are PLENTY of germs in the public library.) Anyway things calmed down in 2024 till end of that year when PMR struck.
Maybe stress of a move by myself to a really new area at the tender age 69/70? & new germs? The vaccines?
You’re right who knows.
Just face forward.

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@kare1
Exactly! We have PMR. Maybe it's the result of a perfect storm of virus, stress and age. No matter how we got it, we have to deal with it and move forward.

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Profile picture for kjoed53 @kjoed53

@kare1
Exactly! We have PMR. Maybe it's the result of a perfect storm of virus, stress and age. No matter how we got it, we have to deal with it and move forward.

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@kjoed53 I would add a fourth factor. None of us is the body you find in an anatomy book. Each body is unique from birth in many ways. As you age you find out how true this is. A physician is not a diagnostic machine you put on your car, nor is your body that car, and that's the challenge of diagnosis and treatment. E.g. hair loss can be from body temperature, so hair loss can start with PMR , as mine did, not from starting prednisone . "Chicken or the egg?"

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Profile picture for vjm0223 @vjm0223

@kare1 yes it was. The study isn’t suggesting pmr is caused by the vaccine, but triggered by it due to the spike protein causing a high immune response.
Weren’t we told that the spike protein cleared our system after a certain amount of time? Well they found it in the placenta of a woman who had the vaccine some time before she got pregnant and then gave birth.
That made me think about the fact that I got the initial vaccine and the booster then the next one we were supposed to get then the booster. So I’ve had 4 shots since covid started. Haven’t had any since I think 2021. Was that spike protein still present when I was diagnosed with pmr in 2025?

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@vjm0223 I think you are on to something. It’s believable and I hope they continue to study it.

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Profile picture for kjoed53 @kjoed53

@kare1
No one knows the cause of PMR. Viruses are suspected of being capable of triggering an immune response that can cause other disorders. Our immune system needs a trigger before it can short circuit and work against us. Maybe the trigger for PMR is a virus, maybe it's a vaccine, maybe it's traumatic stress or maybe it's the way our immune system ages. No one knows. Our symptoms and pain levels vary from person to person, so why should we expect the same cause?

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So agree! My family has a genetic predisposition (HLA D4) to many types of autoimmune diseases such as Type 1 Diabetes, celiac disease, Sjogrens , and PMR. We can pinpoint viral illness about 6 months prior to Type 1 dx in two family members. My trigger for PMR seems to be stress. Not one answer for all cases

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