I like to hear your story about fasting, fasting mimicking and Cancer

@isadora2021

As a retired chemical engineer, I am also skeptical of diets and supplements that claim effectiveness against cancer, without human clinical trial supporting the claims.

That’s why my main intervention (I’m on active surveillance for localized prostate cancer) is based on the ERASE randomized clinical trial.

The conclusion of the ERASE randomized clinical trial is as follows;

“The ERASE trial demonstrated that HIIT increased cardiorespiratory fitness levels and decreased PSA levels, PSA velocity, and prostate cancer cell growth in men with localized prostate cancer who were under active surveillance.”
https://jamanetwork.com/journals/jamaoncology/fullarticle/2783273
After 2.5 years of implementation of the ERASE trial protocol, my PSA density and PSA velocity are both moving in the negative direction and serial mpMRI’s have just recently indicated that all three of the original PIRADS lesions, found when I was diagnosed in October 2023, are no longer visible.

My VO2 Max has increased from 39.5 to 48.5, I’ve lost 30 lbs, my HDL has increased from 30 to 50, I no longer use (after 17 years) a CPAP machine for sleep apnea and all chronic inflammation joint pain is gone.

I’ll be 70 y/o in June and I can truly say that the human based ERASE randomized clinic trial results have proven to work in my case.

@handera Thanks so much for sharing this information. I had read that HIIT increases mitochondrial function which is the key to your immune system so the fact that it is helping you is wonderful news.
Recently I have increased my walking speed with light hands weights to get into the HIIT zone, it works and boy do I feel great afterwards.
Your positive results with HIIT make me think I am on the right track. The Keto and metabolic diets are just too hard to maintain long term and probably only good for certain types of cancer while HIIT is great for all of them.
There is a lot of research by Dr. Valter Longo on the Fasting Mimicking Diet when used during chemo treatments but not sure in the long run, once you are out of treatment how much it benefits us.
Thanks again, you made my day:)

@beebe

…as encouragement…I could barely slow jog around a 400m track for one lap when I first started running at age 66….I had to stop and walk after that slow one lap jog. I had never run a 5K distance in my entire life up until I started at age 66.

I started with a VO2 max of 35…just yesterday (I’ll be 70 in June) my VO2 max increased to 49.

Now I run three Zone 2 5K’s per week on a rubberized track and finish with two 0.25mile HIIT runs. Zone 2 running (70-75% of max heart rate) is totally sustainable and it’s absolutely incredible the long term impact.

IMHO diet and fasting help; but this aerobic protocol is proven via randomized clinical trial, in just 12 weeks effects appear (I’m 2.5 years into my dedicated protocol).

The problem is that it takes months and years and an absolute commitment to consistent implementation, which (unfortunately) many are just not willing (some truly unable) to do.

The most important thing, as one begins, is joint safety and running consistency, leaving one day of rest between aerobic running days. I wear Hoka Bondi 8’s, two pair of low cut socks and ALWAYS run on a rubberized track. I have never had a joint injury, or even a toe blister!

My average heart rate has dropped dramatically (see attachment) for my runs. This is because old mitochondria are destroyed and new (and many more) replace the old in both your heart muscle and leg muscles…I believe this same process slows (and eventually stops) cancer cell growth and progression.

All the best!

@handera joint replacements prevent me from running. The one in my foot will throp for hours after even a slight run, but I have a spin style stationary bike. Interval training is my favorite thing to do on the bike. I get really board with it though.

@handera joint replacements prevent me from running. The one in my foot will throp for hours after even a slight run, but I have a spin style stationary bike. Interval training is my favorite thing to do on the bike. I get really board with it though.

@beebe

…as encouragement…I could barely slow jog around a 400m track for one lap when I first started running at age 66….I had to stop and walk after that slow one lap jog. I had never run a 5K distance in my entire life up until I started at age 66.

I started with a VO2 max of 35…just yesterday (I’ll be 70 in June) my VO2 max increased to 49.

Now I run three Zone 2 5K’s per week on a rubberized track and finish with two 0.25mile HIIT runs. Zone 2 running (70-75% of max heart rate) is totally sustainable and it’s absolutely incredible the long term impact.

IMHO diet and fasting help; but this aerobic protocol is proven via randomized clinical trial, in just 12 weeks effects appear (I’m 2.5 years into my dedicated protocol).

The problem is that it takes months and years and an absolute commitment to consistent implementation, which (unfortunately) many are just not willing (some truly unable) to do.

The most important thing, as one begins, is joint safety and running consistency, leaving one day of rest between aerobic running days. I wear Hoka Bondi 8’s, two pair of low cut socks and ALWAYS run on a rubberized track. I have never had a joint injury, or even a toe blister!

My average heart rate has dropped dramatically (see attachment) for my runs. This is because old mitochondria are destroyed and new (and many more) replace the old in both your heart muscle and leg muscles…I believe this same process slows (and eventually stops) cancer cell growth and progression.

All the best!

@handera
Very impressive improvements. It is great you have kept track of your progress. Have you made any diet changes along with the HIIT?

@beebe

For the first 3 months (after diagnosis) I went vegan to reach my target BMI of 22.5-23.0; which I now have maintained for the last two years.

Once I reached my target BMI, I brought salmon, chicken and grass feed beef back into my diet.

I retained the things I really enjoyed;

- two teaspoons of ceremonial grade Matcha tea and my own Ezekiel bread for breakfast

- dark berries with fruit juice smoothie for lunch

- 1 cup of mix of homegrown broccoli/ kale/ radish sprouts with whatever we’re eating for dinner

I occasionally make a “veggie chili with chicken” for dinner.

My one “cheat” is a glass of red wine with red peppers and carrots and hummus and spicy cheese with whole wheat crackers….every evening!

I find that if you don’t like “what’s good for you”, keep trying until you find things for which you enjoy….it’s the only way to sustain a “good diet”.