Hi @asarnesejr - yes, I have some thoughts:
1. Your low grade MDS with only germline and somatic DDX41 mutations looks very favourable in terms of prognosis and treatment.
2. However, for your level of blasts, your blood readings look low. I have comparable ones for neutrophils, monocytes and platelets, but I’m at a more advanced stage - AML (and more mutations too).
3. Moreover, in your case, not only myeloid lineage is adversely affected, but also the lymphoid one. So, both parts of the immune system - innate (including neutrophils and macrophages) and adaptive (including T and B cells) - are somewhat compromised. And now (hopefully temporary) reduction in RBC and haemoglobin (which can lead to mild anaemia) - this though can be also related to your levels of B12, folate and iron. These observations brins me to the next 2 points.
4. As mentioned before, you need to get clarity about your chemo treatment and HSCT (most likely unrelated donor given germline). You may or may not need it soon, but such clarity and readiness are important at this stage.
5. Given point 3, you might also need to rethink whether such endeavours like holidays in Disneyworld is a good idea. I have to say though that, to these days, I lead a normal life, including a number of very long distance trips. However, in my case, it was against my doctor’s advice (but he still was very helpful and provided me with the right antibiotics and other medicine given my need to travel).