Reclast infusion side effects?

Below is a more recent paper (2023) than the one from 2011 that @daisy17 linked. There is lots of active research in osteoporosis and the 2023 paper also supports her comments. It has great discussions and a table of relative risk (RR) vs absolute risk reduction (ARR).
https://www.amjmed.com/article/S0002-9343(24)00101-3/fulltext.
Excerpt: "... For patients at high risk of fracture, especially those with prior fractures, treatment with bisphosphonates is well supported by clinical evidence that may underestimate benefits; however, for patients with osteoporosis based on bone density alone, treatment benefits are less certain. ..."

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!

Sorry for your suffering and hope you feel better….i just read that if a person has kidney issues, Reclast can cause serious damage….other OP meds not so much..it’s really hard to balance the needs of aging bones and aging kidneys !

@nycmusic I’ve always found it amazing how a medication can take care of one issue and yet cause so many other problems, yet we are willing to take the medication for hopefully immediate relief only to find additional problems down the road from that medication!

@dannyandebbie Well said, and can be true of various diets as well…can be a real problem with supplements and some alternative ‘’meds’’…balance is key, and patients need to be proactive in partnership with good docs..

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!

@nycmusic
According to the majority of endocrinologists, the only solution, for non oral takers of these ‘good meds’, is RECLAST.
I wish there were more research and openness to “alternative” options for our bones so we can age pain free.
We have serious side affects from this medication, and no one, tell me if you know one, doctor in the endocrinology dept, acknowledging it.

Hello,
I’m new to this forum.
I had a Reclast Infusion in May 2025. After a year dealing with knee pain issues my Dexa Scan results were terrible.
My endocrinologist had already suggested I’d need it, after doing some research I refused it for about 5 years.
Since the infusion, I’ve had digestive problems and pain on my left ribs. Strangely, on the first 24 hours after the infusion this is the exact place where I had intense sharp pain. It’s mostly during the night and in the morning.
Anyone experiencing the same?
Thank you!

2 weeks before I was due for Reclast infusion I learned I needed a tooth extracted and a bridge put in. The endocrinologist said to not reschedule Reclast until all the dental work was completed. I come from a family of dentists and dental hygienists. They have all told me NOT to do Reclast. Even the oral surgeon that extracted my tooth was lecturing me (angrily) on not doing it. I have a temporary bridge right now and soon getting the permanent one put in and I have had a lot of time to think about Reclast and decided against it. The risk isn't worth the reward bcz there doesn't seem to be any reward in doing it! When I first saw my endocrinologist she asked me if I had heartburn or stomach issues and bcz I said I had heartburn she said I have no option but to do the Reclast. I am weary of this response also. How bad are the oral meds for us folks with occasional heartburn? Are the endocrinologists told to push the Reclast on their patients?
I have a bone scan and appointment with endocrinologist in May and at that time I have to re-evaluate this whole situation. I am having a hard time believing that there is a medication that can restore bone health. Can anyone make me a believer?

2 weeks before I was due for Reclast infusion I learned I needed a tooth extracted and a bridge put in. The endocrinologist said to not reschedule Reclast until all the dental work was completed. I come from a family of dentists and dental hygienists. They have all told me NOT to do Reclast. Even the oral surgeon that extracted my tooth was lecturing me (angrily) on not doing it. I have a temporary bridge right now and soon getting the permanent one put in and I have had a lot of time to think about Reclast and decided against it. The risk isn't worth the reward bcz there doesn't seem to be any reward in doing it! When I first saw my endocrinologist she asked me if I had heartburn or stomach issues and bcz I said I had heartburn she said I have no option but to do the Reclast. I am weary of this response also. How bad are the oral meds for us folks with occasional heartburn? Are the endocrinologists told to push the Reclast on their patients?
I have a bone scan and appointment with endocrinologist in May and at that time I have to re-evaluate this whole situation. I am having a hard time believing that there is a medication that can restore bone health. Can anyone make me a believer?