I am taking Danziten but I have a different issue so I’m not sure if I will be helpful or not. It sounds like you’ve taken tasigna or the generic nilotinib maybe. Have you?
I just started Danziten but it’s been about two weeks now and I feel horrible. Horrible headaches. I’m so tired. I can barely function and my muscles hurt all over. If I lift something that literally weighs 5 pounds the next day my muscles are so sore like your muscles would be if you did a new intense workout that your body isn’t used to. The problem is I was on tasigna and I was not very compliant a lot of times because of the fasting restrictions so then when I learned about Danziten I immediately wanted to switch. I am on the proper dose conversion. Which is 190mg Danziten as I was on 400mg tasigna. And they say the side effect profile is the same so this doesn’t make sense. I think the hard part is as we know Medicine unfortunately a lot of times tend to treat. Everybody textbook and people are not the same and unfortunately Danziten hasn’t been around very long so there aren’t a ton of studies, but I am wondering if there is a possibility that I am absorbing this medication much better and maybe need a lower dose. I did really well on nilotinib and was even in MMR for several years until I became non compliant because I’m sick of the fasting nonsense so I was obviously absorbing the medication OK but I’m just wondering if it’s possible the equivalences aren’t equivalent for me because I don’t understand why I would be having these bad side effects to Danziten that weren’t this bad on tasigna.
The other thing I will know is that I have been completely off of my medication for a couple of months because of this new horrible pharmacy, benefits manager that refused to approve the medication stating that it wasn’t medically necessary but anywho I came completely out of remission, even on a hematology level. My CBC and platelets, everything are elevated. However, I went off of my tasigna for 9 months to have a baby and when I went back on it I wasn’t this sick with this bad side effects after having a much longer medication break