My turn ~ Another view on Reclast [Zoledronic acid aka Zometa]

@ginger1957 actually I'm almost back to normal!!!!! Body aches are at a minimal!! Only advice I could give you is to hydrate well 2-3 days before your infusion of reclast and on the day of your infusion to take 2 extra strength Tylenol and I also followed the others on this chat to take a Zyrtec and I drank 64 0z of water also. My infusion took 45 minutes and at the end a saline flush. If they don't offer that fir you ask them if you could get a saline flush.. hopefully your in the 97% with no side effects! You got this!!! Please keep me updated on how you do okay??

@jimmy05 Sorry you are experiencing these troubles. Quick note on supplements. You may want to include Vitamin K2(M-7), which directs the calcium to the bones rather than having it go straight to the bloodstream. There’s been a lot of discussions about supplements here. Good luck.

@jimmy05
How are you doing now? I surely hope you are feeling much better, I have my first Reclast infusion on Thursday the 26th. 🤞🤞

I feel back to normal!! Your going to do great I have that feeling!!! Staying hydrated 3-4 days leading up to your infusion and 5 days after the infusion!!! Thank you for checking in!! Please post and let me know how your infusion went. I'll be praying that it goes well for you!!!

@carolynk - Thank you so much for sharing your experience — I truly find it encouraging. I’m 71 as well, and I’m scheduled for my first Reclast infusion tomorrow. I have to admit, I haven’t been able to stop thinking about the possibility of major side effects.

Up to this point, I’ve been fortunate not to have had any significant medical issues. However, I did fracture my wrist last year after missing a step while showing a home to one of my buyers (I’m a Realtor).

I’ve spoken with a few friends who have had the Reclast infusion and experienced no major issues. They’ve encouraged me to move forward, which has been reassuring. Unfortunately, they live in another city and state with access to excellent medical facilities and services.

No one from the medical staff has spoken with me yet about what to expect when I arrive at the facility. Still, I’ve done quite a bit of reading and feel like I have a general idea of how things should go. I’m staying prayerful and hopeful that I, too, will have a positive experience — one that I can share to encourage someone else.

Can someone tell why Tylenol seems to be the go-to with the Reclast, instead of Aleve? Tylenol never worked for me when I've needed relief.

I had my Reclast infusion last Thursday. I felt great the following day and 1/2 into Saturday and I suddenly became very congested as in a very bad cold. Body aches, headache followed. Both continued and today seems to be resolving, I hope. I had prepped according to a post her regarding hydration, Tylenol and antihistamines. I had asked my endocrinologist for help with the 1/2 hour hydration before and after and ws told they have never heard of this. I suggested someone call the U of Kentucky to ask what their protocol is. I didn't anticpate that I would get any support from this doctor or his PA. It's important to advocate for ourselves even when it doesn't help. I am grateful for the help I have found here. My sympotms have not been of the type that I regret having the infusion. I will have the next one in one year. Thank you all~

@tinylu
It looks as if there could be an interaction between Aleve and Reclast so it's best to discuss this with your doctor first. You can search for Aleve and Reclast interactions and will find information, but here is one from drugs.com:
https://www.drugs.com/drug-interactions/ibuprofen-with-reclast-1310-0-2331-10724.html
It is not recommended to take Aleve (a nonsteroidal anti-inflammatory drug) with Reclast (zoledronic acid) due to the increased risk of gastrointestinal issues. Consult your healthcare provider for safer alternatives for pain relief.
Wikipedia cancercareontario.ca.

@tinylu, it is because of the risk to the kidneys with both medications.

@clj9821 I am new to this forum and so appreciate all of the information and shared experiences from all of you. I met with my endocronologist this afternoon and she wants me to get the Reclast infusion. I tried Fosamax a couple of years ago and after a couple of weeks, had such horrible abdominal pain I passed out and fell. Fortunately I didn't break any bones. I swore off any meds until I had my next DEXA last July and with a -4.2 T score in my lumbar spine, I was forcefully encouraged to try Evenity. I had my first injection on a Friday and Sunday I was in the ER with heart attack symptoms. Those cleared up so I had another injection 6 weeks later (typically 4 weeks but because of my first reaction, endo decided to wait an extra two weeks). I had such severe bone pain I couldn't even walk. I have had 3 total knee replacements (same knee) and a hip replacement so I know something about pain, but the bone pain from the Evenity was so much worse than post-surgery pain. So I quit the Evenity in Decemer. I am terrified of getting the Reclast infusion because of my history with side effects. My endo says she understands my hesitancy, but that since I am at such high risk, I really need to take something because I will continue to get worse and it is not a question of "if" but "when" I will have a fracture. I am otherwise in perfect health. I hike daily, lift weights and am very fit at 66 years old. My endo also thinks I will tolerate the Reclast better than Fosamax because it is infused and thus bypasses the digestive system. Based on what she told me and what I've read here, I guess I will close my eyes, hold my nose, and take the jump and pray the side effects will be managable and that my next DEXA will show improvement. I hope everyone continues to get better and stronger.