Anyone else "mourn" their NO-MEDS SELF before a STATIN?

Posted by lilac2025 @lilac2025, Feb 1 1:51pm

Hello all. I'm about to join the millions of people who are on a statin. This is something I've resisted for over a year after learning about my calcium score of 149, which put me at a "moderate" risk for an event in the next 10 years and in a high percentile. I looked into it deeply and looked at myself as a whole person, not someone who has a number and is part of a statistic. I have eaten a plant-based diet for over 30 years, but still, despite all my efforts at a healthy diet, plus losing 30 pounds and regular exercise, I cannot get my LDL lower than 108. And, a Cardiac CT Scan (with dye) in December showed I have a "moderate" plaque burden, though I had 0 "low attenuation" plaque, which is apparently, the most dangerous, ready to erupt kind. Still, I learned I had narrowing in a major artery - up to 40%, which isn't severe, but if I do nothing, it will just get worse. THAT is concerning! This finding has given me the impetus to go on the statin. It's genetics. I cannot control it. I've tried. I am throwing in the towel, so to speak, and allowing modern medicine to give me that "nudge" I need to lower the LDL. It feels too risky to go without doing so, at this point. Of course, I'll still eat healthy & exercise, as statins only lower the risk by 25%, anyhow. All my other LIPID numbers look good and my total cholesterol is at 189 or thereabouts. Still, the proof was in the images and the Cardiac CT Scan FFR readings of how much plaque is in each coronary artery. Without going into those details, I cannot fight the issue my liver is having with processing cholesterol. It isn't doing it well, despite how hard I've tried to "make things better" through weight loss, exercise & a whole-food plant-based diet. I've already gone through my "mourning" phase of the old, "natural" me who did everything she could to lower my cholesterol, from drinking chia/flax and soy milk before bed, to giving up all seed oils, you name it, I've tried it. I eat tons of vegetables (salads), fiber-filled meals (like lentils soups), oatmeal with fruit daily, etc. I just hope I will do okay without side effects on the 5 mg. of Rosuvastatin I'll be starting (either tonight or tomorrow). I've read one too many stories about muscle pains, brain fog, etc., but my cardiologist told me NOT to worry about side effects, so at this low dose, I will put that out of my mind and go for it. I want to live a long life and if this helps me do so, I will now embrace the science behind these statin medicines, which have been around for decades. I feel hopeful that without my LDL being sky high, this low dose will do the job. I need to get it to 70 or below. Is anyone else in my position? Is there anyone out there who has had to recently start a statin after trying everything they possibly could through diet & exercise to lower their LDL? Were you sad for awhile? I'm okay now, as I've had over a month to adjust to this. I started a BP medication in early January, and so far, I've adjusted well to that (Losartan, 25 mg). I didn't want to start two new medicines at once. FYI, I'm a 66 year old woman, weight about 147, and am 5'5", if that gives further perspective. Being post-menopausal is a large part of these changes, but that's for another discussion!

If you've had a bad experience while on Rosuvastatin, it would NOT be helpful to me to share that. I've already had to get over my fears about that and I have now. Rather, I need support right now. If you've had a POSITIVE EXPERIENCE, which has lowered your LDL while on Rosuvastatin, at any dose, without any side effects, I'd also love to hear your story about that!

Interested in more discussions like this? Go to the Heart & Blood Health Support Group.

Profile picture for seniormed @seniormed

I resisted statins for years with borderline cholesterol and my very healthy lifestyle to bank on Now I know better. They don’t just work on cholesterol metabolism
there are other beneficial effects.
CoQ10 is another underrated supplement that does more than just counter side effects of statins.
A carotid ultrasound can be important in our risk evaluation for soft plaque.
Keep up your healthy discipline and your vitamin D levels.

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@seniormed Hi and thank you for your reply. I guess there does come a time when we, as humans, do all we can, then at some point, realize that there may be things we just cannot control and to allow modern medicine to help us out. I'm glad you also reached that conclusion.
I also take CoQ10, and had started that even before the statin. I recently DID get the CIMT ultrasound (Carotid Inter-Media Thickness) done and will find out what my plaque burden is in my neck. I'm a bit nervous to find out about that, but at least I am on the rosuvastatin in case it ends up matching my moderate plaque burden in my heart arteries. I do take Vitamin D, as well Vitamin K-2 M-7. I also take a Multiple Daily and Vitamin C. Thank you for your encouragement and support! Take good care! Keep up your own good work on your health!

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Profile picture for carlnh @carlnh

I may be abot to join you on the statin train... Never had high cholesterol or any symptoms of heart issues normal weight, lots of exercise, good physical condition at 79 yo, But, have family history of cardiac disease. So, asked my PCP if there are any tests I should have done to assess any potential issues. She recommeded a CAC which I had done with a result of 491 which is 85th percentile. We were both shocked! She then ordered a stress echocardiogram which was totally perfect. Anyway, I will see a cardiologist for the first time soon and thinking he will prescribe a statin. Very concerned about side effects as I'm very physically active and, yes, having never been on any kind of drug, will miss my "no drug" status. But given all that, I'm willing to give it a go if that's what the recommendation turns out to be. Also going to ask to have a CCTA done to assess exactly what blockages I may have. Best of luck on your journey!

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@carlnh Hi Carl. Thank you so much for sharing your story, and I apologize for the delay in responding. Maybe we'll sit next to each other on the "statin" train (I loved that colorful language!) and have a lively discussion! Perhaps the ride will be smooth and pleasant. 🙂 I totally sympathize with your shock with your Calcium score, as that was the same with me in November 2024, when I learned mine was 149. I resisted until the Cardiac CT Scan, as my story describes. The images really don't lie. I hope you don't have any blockages. I didn't, but I did have "narrowing", as you know, so that's what led me to try to slow down the progression of any further narrowing, if possible. I want to reassure you that at least for me, so far, on DAY 7 of the rosuvastatin, 5 mg. I have no side effects. I've also heard that people, like you, who exercise regularly and are active, create collatoral arteries that make up for others. I don't have all the scientific/medical information at my fingertips, but I thought it was very interesting how the heart manages to adapt. Thank you for the well wishes and I also wish all the best to you, as well! Please let me know how you're doing.

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Profile picture for lilac2025 @lilac2025

@jlharsh Hi Janell. I've been meaning to reply to your comment, which I appreciate beyond you can imagine! Thank you for pointing out that all my efforts weren't for naught and that it helped me get to this age. I like to think it did. Today marks Day 7 on Rosuvastatin, and so far, none of those muscle aches some people experience. It's also Week 6 on Losartan. Between the 5th and 6th week, on Feb. 9th, I did feel dizzy when I went to a laying down position for the first time. I was actually getting my Calcium Score checked again so I see what is BEFORE the statin does its job. (That's for another post!) It was in the morning before my coffee. I do NOT experience any dizziness getting up out of bed in the middle of the night, getting up from a chair, etc, so it's possible I was somewhat dehydrated.

It's very reassuring to me to hear your story that you've been successful on rosuvastatin. I'm really happy for you! I agree with your approach and am hoping that the 5 mg. of rosuvastatin will do the trick for me, but if it doesn't, I will ask for Ezetimibe rather than increasing the rosuvastatin. Of course, I'll continue with my plant-based diet and regular exercise, and try to reduce my stress!

You asked the reason for the Cardiac CT Scan. I feel rather fortunate that I was able to get such a detailed and thorough test. It was because before I knew 100% I had gastritis, I had some pain/tightness around the braline. My doctor was pretty sure it was gastritis and I did take medication for that. Howevver, to be 100% sure and put me at ease, she suggested I get a Nuclear Stress Test. (treadmill). Well, I had that done, no problem, no chest pain, EKG was A-OK, but the results showed an abnormal perfusion in an area. My cardiologist said there are sometimes FALSE POSITIVES, and suggested I get the more accurate, detailed Cardiac CT Scan. So, there you go! I'm glad I got it as that was the deciding factor for me. I am very well aware that high blood pressure damages the lining of your arteries and allows plaque to get inside. I've always been high normal or Hypertensive 1, so I'm not playing around anymore with that. I am hoping it will come down. It's usually in the 130's over 90's.

Thank you again for your response!! I very much appreciated it.

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@lilac2025, it sounds like you are working with a good care team to make sure you live your best life. Kudos! I am glad to hear you are tolerating your medications at this point.

I am interested to follow how you are doing with your testing, cholesterol treatment and general health. Will you come back and comment when you have updates? When will you test your LDL now that you are taking rosuvastatin?

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I would start either Praluent or Repatha both being PSK9 inhibitors. My LDL has been as low as 7, Tchol 83, HDL 80 as I am attempting to lower my Arterial Calcification.
I also take Ezetimibe 10 mg, ,Rosvastatin 10 mg, Repatha 140mg per ml, amlodipine beslate 5 mg, spiroactalone 100 mg,81mg enteric aspirin bid

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I am an 81 years old man. I have been eating a vegetarian diet and running for for many years. I have high cholesterol. The doctors wanted me to take statins but I refused. My mother was put on statins and had severe muscle pain. About a month ago I went to bed with zero problem. However, I woke up, about 8 AM, with a very severe back ache. I began to take Tylenol for the pain. The pain continued and I continued to take the Tylenol. Then after about 3 weeks, I went to the doctor for a checkup, and tests. He could not find any issue. He was a new doctor and recommended statins. We had a good discussion. He said his dad takes statins and with my high cholesterol he strongly recommended I take them. I agreed and asked him to write me a prescription. Here is the reason I am writing this comment. I got his prescription of Atorvastatin, 80 mg pills. I took one pill that night, then the next night I took another pill. When I woke up the following morning the back pain was gone! I stopped taking the Tylenol. I continue to take the Atorvastatin pill at night and the pain remains gone. I have discussed this with two doctors, neither has ever heard of this happening before. Let me be very clear. There is no doubt in my mind that the Atorvastatin cured the back pain. Experimental evidence.

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Profile picture for poppy0344 @poppy0344

I am an 81 years old man. I have been eating a vegetarian diet and running for for many years. I have high cholesterol. The doctors wanted me to take statins but I refused. My mother was put on statins and had severe muscle pain. About a month ago I went to bed with zero problem. However, I woke up, about 8 AM, with a very severe back ache. I began to take Tylenol for the pain. The pain continued and I continued to take the Tylenol. Then after about 3 weeks, I went to the doctor for a checkup, and tests. He could not find any issue. He was a new doctor and recommended statins. We had a good discussion. He said his dad takes statins and with my high cholesterol he strongly recommended I take them. I agreed and asked him to write me a prescription. Here is the reason I am writing this comment. I got his prescription of Atorvastatin, 80 mg pills. I took one pill that night, then the next night I took another pill. When I woke up the following morning the back pain was gone! I stopped taking the Tylenol. I continue to take the Atorvastatin pill at night and the pain remains gone. I have discussed this with two doctors, neither has ever heard of this happening before. Let me be very clear. There is no doubt in my mind that the Atorvastatin cured the back pain. Experimental evidence.

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Wow, @poppy0344! Your experience with statins helping you is straightforward and so, so helpful. It sounds like much more may be learned about statins.

My first cardiologist told me in addition to lowering cholesterol statins also reduce inflammation. This seems in line with what you are experiencing, reduced back pain after starting atorvastatin. I have had experiences similar to yours with medications including cholesterol drugs. Most recently, I had my 5th or 6th injection of Inclisiran (every 6-month schedule). I went through a couple nights of pain with the first, then a little lessened with the 2nd. Following my most recent injection I experienced noticeably 2 days of pure comfort.

I am also taking a statin I had quit 20 years ago, I thought because of pain. One thing different with me now is an improved lifestyle, activity and diet. You mention a lifetime of healthy lifestyle. I would think the healthier our bodies are the better any drug would work in our bodies. I am not a trained medical professional so I don’t know. It just seems realistic this would be one factor, and my experience would seem to support it. It sounds like yours, too.

Statins work through the liver so there may be something there as well. It will be interesting to see how you continue to feel. I hope you come back and provide updates.

When do you get your lipid numbers checked to know how well the Atorvastatin helps manage cholesterol?

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