Transdermal HRT

Posted by vkmov @vkmov, Oct 19, 2023

Many studies have found that transdermal HRT protects and builds bone without all the horrific side effects of many first-line osteoporosis treatments. The patch bypasses the liver and thereby avoids the risks of breast cancer, strokes, etc. Has anyone explored this or discussed it with their doctors?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Profile picture for humphreysbr @humphreysbr

@seapen just my two cents but I was on HRT and experienced breast tenderness and within a year I had a callback from my mammogram. The estrogen had stimulated abnormal excessive growth in my mammary ducts. I had a biopsy and subsequent lumpectomy to get rid of tve area of abnormal growth. Known as Atypical Ductal Hyperplasia (ADH) and can become a precursor to breast cancer. The breast tenderness is an effect of the estrogen and may indicate the dosage is too strong. Check with your doctor.

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@humphreysbr I am very interested in trying HRT, if I can approved, so I can avoid a lifetime of osteop meds. I have already been on Evenity for a year and Prolia for a year. My Dr. is recommendeing Reclast next which scares me. Now that the blackbox warnings for HRT have been lifted, I'd like to see if I can get a patch. I am a 33 year breast cancer survivor, had a unilateral masectomy as well as a hysterectomy 10 yrs ago. My OBGYN will not prescribe HRT for me. however the new evidence shows that low dose patches are not contraindicated. What you are reporting may mean there is still a risk.

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My situation exactly. You might want to consult with a menopause expert who will evaluate you for HRT as an individual.

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Profile picture for tillymack @tillymack

My situation exactly. You might want to consult with a menopause expert who will evaluate you for HRT as an individual.

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@tillymack I never heard of a menopause expert. Would that be an OBGYN?

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Could be that or other specialty that has special interest or training.

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Profile picture for gretch19 @gretch19

@tillymack I never heard of a menopause expert. Would that be an OBGYN?

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@gretch19

Could be a gyn or endocrinologist or you might have to seek a functional medicine provider. If all women ask them they may begin to pay more attention to our needs

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Profile picture for gretch19 @gretch19

@tillymack I never heard of a menopause expert. Would that be an OBGYN?

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@gretch19
You may find a hormone specialist who uses hormone testing and BHRT, bioidentical hormones, by calling your local compounding pharmacist.
ZRT also has a provider search with a variety of pharmacies and doctors:
https://myzrt.zrtlab.com/tools/findprovider

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I have used BHRT and strontium citrate for years.
Osteoporosis is no longer my diagnosis; my bones and my microarchitecture are in the normal range as per dexa and TBS. No side effects, no fractures. My dexa tech told me that I one of only 2 people whom she has seen in a 20 year profession who no longer have osteoporosis.
There is a community of people on Inspire who use strontium citrate with good results. There are several research articles that show hormone therapy to be comparable in many osteoporosis drugs. Several menopause associations now recommend hormone therapy .
https://www.inspire.com/m/Kathleen1314/journal/d69831-strontium-users-stories-3-alternative-to-pharma-meds/
Indeed, major organizations like The Menopause Society and the Royal Osteoporosis Society recognize that Menopausal Hormone Therapy (MHT) is an effective option for preventing bone loss and reducing fractures in postmenopausal women. It is often considered comparable in efficacy to bisphosphonates for fracture prevention in women under 60 or within 10 years of menopause.
https://theros.org.uk/information-and-support/osteoporosis/treatment/hormone-replacement-therapy/?,for%20these%20symptoms%20to%20improve.
https://menopause.org/wp-content/uploads/press-release/hormones-bone-mineral-density-osteopenia-and-osteoporosis.pdf

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Profile picture for gretch19 @gretch19

@humphreysbr I am very interested in trying HRT, if I can approved, so I can avoid a lifetime of osteop meds. I have already been on Evenity for a year and Prolia for a year. My Dr. is recommendeing Reclast next which scares me. Now that the blackbox warnings for HRT have been lifted, I'd like to see if I can get a patch. I am a 33 year breast cancer survivor, had a unilateral masectomy as well as a hysterectomy 10 yrs ago. My OBGYN will not prescribe HRT for me. however the new evidence shows that low dose patches are not contraindicated. What you are reporting may mean there is still a risk.

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Hello @gretch19,
I had my first endocrinologist visit this week. He told me that if I or anyone in my family had ever had breast cancer or ovarian cancer, I would not be a candidate for HRT of any kind. Sorry for this news, but it's just one doctor. If you can find another doctor to prescribe HRT for you, maybe they will tell you something different. Good luck!

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My endocrinologist just prescribed the HRT transdermal patch for me and oral progesterone. The progesterone is called micronized progesterone. I am 72. I suggest watching Margaret Martin's interview with Dr. Susan Ott. Just google that. That video has a ton of information, including a section on estrogen for osteoporosis with graphs of fracture incidences. Very scientific. Then google Dr. Susan Ott. (There are two women of this name, but only one is in the osteoporosis field. Her website isn't pretty, but there's a ton of information. My endocrinologist also said that it is not true that women lose 6% of bone a year. I asked him about that twice during our appt. Apparently, a lot of misinformation propogates all over the internet for years, and everyone believes it. I was relieved to hear that... good luck! Oh - I meant to say that you hear that if you're older, like me, estrogen won't help you anymore, unless you started in your 40s or 50s, etc. But Dr. Ott's work shows us that it will help at any age.

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Profile picture for mcchesney @kathleen1314

@gretch19
You may find a hormone specialist who uses hormone testing and BHRT, bioidentical hormones, by calling your local compounding pharmacist.
ZRT also has a provider search with a variety of pharmacies and doctors:
https://myzrt.zrtlab.com/tools/findprovider

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