Has anyone done only 4 Pluvicto treatments & saved 2 for later?

Posted by deltadawn78 @deltadawn78, Jan 12 3:57pm

Anyone who has done 4 Pluvicto treatments and save the last two for a later time? If you PSA has gone down 70% in just one treatment and is at 3.9 waiting for results of second treatment and PSA results this week. Wouldn't it make sense to give your body a break? Thanks.

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The guy who hosts the Reluctant brotherhood advanced prostate cancer forum had two Pluvicto treatments and his PSA went down to .05 so he’s holding the last four off for later.

All different types of this combination are done,

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Profile picture for jeff Marchi @jeffmarc

The guy who hosts the Reluctant brotherhood advanced prostate cancer forum had two Pluvicto treatments and his PSA went down to .05 so he’s holding the last four off for later.

All different types of this combination are done,

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@jeffmarc Thank you so much! My husbands doctor wants to give him all 6 right away. He does not have an open mind. I will open it up for him.

Dawn

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I had 3 Pluvicto treatmentsand my cancer spread and psa sky rocketed.
I was sent directly to chemo where i am about to receive my 3rd dose.
Really disappointed that pluvicto did not works and i had to quit

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Profile picture for tree2 @tree2

I had 3 Pluvicto treatmentsand my cancer spread and psa sky rocketed.
I was sent directly to chemo where i am about to receive my 3rd dose.
Really disappointed that pluvicto did not works and i had to quit

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@tree2
Pluvicto Works really well for 1/3 of people, OK for 1/3 of people, and not at all for 1/3 of people.

Sure wish it worked better for everyone.

There are genetic reasons it doesn’t work.

Pluvicto genetic issues. Somatic or heditary. You can get a hereditary genetic test To see if you have any of these. You can also get a somatic test on blood or metastasis tissue to see if your metastasis have resulted in a change in your genetic makeup.

RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

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I've had three Pluvicto treatments. PSA of 22.3 has dropped to 11.2 to 6.6 and then to 3.8 after the 3rd round. I have the 4th treatment coming up next week, and if it drops again as anticipated, we'll bank those last two treatments for when the PSA starts to climb again, or pain/scans indicate it's needed. Like all treatments, there can be many reasons it works for some and not for others. I'm fortunate and grateful that it's giving me more longevity, certainly with a better quality of life than if I were doing chemo at this point. I'm 78, PC since 2008, stage 4 since 2021, and living every day well

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Profile picture for tree2 @tree2

I had 3 Pluvicto treatmentsand my cancer spread and psa sky rocketed.
I was sent directly to chemo where i am about to receive my 3rd dose.
Really disappointed that pluvicto did not works and i had to quit

Jump to this post

@tree2 I am so sorry.

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Profile picture for jeff Marchi @jeffmarc

@tree2
Pluvicto Works really well for 1/3 of people, OK for 1/3 of people, and not at all for 1/3 of people.

Sure wish it worked better for everyone.

There are genetic reasons it doesn’t work.

Pluvicto genetic issues. Somatic or heditary. You can get a hereditary genetic test To see if you have any of these. You can also get a somatic test on blood or metastasis tissue to see if your metastasis have resulted in a change in your genetic makeup.

RB1, PTen, TP53 are Pluvicto resistant
ATM & BRCA work better with Pluvicto

Jump to this post

@jeffmarc Thank you.

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Profile picture for jimw77 @jimw77

I've had three Pluvicto treatments. PSA of 22.3 has dropped to 11.2 to 6.6 and then to 3.8 after the 3rd round. I have the 4th treatment coming up next week, and if it drops again as anticipated, we'll bank those last two treatments for when the PSA starts to climb again, or pain/scans indicate it's needed. Like all treatments, there can be many reasons it works for some and not for others. I'm fortunate and grateful that it's giving me more longevity, certainly with a better quality of life than if I were doing chemo at this point. I'm 78, PC since 2008, stage 4 since 2021, and living every day well

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@jimw77 Thank you.

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Thank you jeffmarc my oncologist is going to push to get the genetic testing done.
Keep up the good fight everyone and know I appreciate all the input

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Profile picture for deltadawn78 @deltadawn78

@jeffmarc Thank you so much! My husbands doctor wants to give him all 6 right away. He does not have an open mind. I will open it up for him.

Dawn

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@deltadawn78 What I would like to know is this: Since Pluvicto treatments cost $50,357.34, will Medicare cover them or are only the rich allowed to stay alive? I ask this because I am tired of researching, finding treatments that are promising and then discovering that they are not covered by my Medicare coverage and Medicare supplement and the treating facility will only treat people that can afford to pay tens of thousands in cash.

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