I have bone on bone osteoarthritis in right hip, waiting for op. I use Flexiseq twice daily on hip and it works wonders. I am able to walk a couple of miles every day and do about 50 exercises stretching etc to keep me fairly fit. It does not contain any drugs as it is sequessomes that lubricate the joint. Would highly recommend to anyone. There are 2 versions, one for joint wear and tear and one for osteoarthritis.