You should consider ITA only if your transplant doctor is informed about what is going on and your oncologist is made aware of the dangers involved after a transplant.

Yes, Zytiga (abiraterone acetate) can have negative effects on the liver, causing elevated liver enzymes (ALT, AST) and bilirubin, which are common but usually managed with monitoring, dose adjustments, or stopping the drug; rare but severe cases of liver failure can occur, highlighting the need for regular liver function tests, especially in the first few months of treatment.
Common Liver-Related Effects
Elevated Liver Enzymes: Increased ALT (alanine aminotransferase) and AST (aspartate aminotransferase) levels are common, occurring in a significant percentage of patients, often within the first three months.
Symptoms: Some people experience jaundice (yellowing of skin/eyes), dark urine, nausea, vomiting, abdominal pain, or fatigue, though liver damage can happen without symptoms.

A couple of articles about this
https://resources.healthgrades.com/drugs/zytiga-side-effects.,abdominal%20pain
https://www.medicalnewstoday.com/articles/drugs-zytiga-side-effects.