Smoldering Multiple Myeloma (SMM). Questions and Answers

Posted by DMD81 @dmdinapoli81, Dec 6, 2025

I wanted to start a discussion specifically on SMM. Asking specific questions about time of diagnosis, like age, m-spike level, protein in urine level and % of bone marrow involvement. If you had MGUS prior to diagnosis? Any bone or joint paint? What your Hem-onc has as your monitoring schedule? Etc.

Interested in more discussions like this? Go to the Blood Cancers & Disorders Support Group.

@jrenjr
Yes, IgG lambda
High risk smoldering mm currently

REPLY
Profile picture for DMD81 @dmdinapoli81

People who are SMM, were you Lambda high or Kappa High?

Jump to this post

@dmdinapoli81 Kappa is high at 227.9 mg/dL with ratio at 15.19 mg/L

REPLY
Profile picture for DMD81 @dmdinapoli81

People who are SMM, were you Lambda high or Kappa High?

Jump to this post

@dmdinapoli81 I forgot to mention SMM is IgA Kappa.

REPLY

2016 - Diagnosed with Non Hodgkins Lymphoma, involving the IgM.
2025 - Recently diagnosed with Multiple Myeloma, involving the IgA. Treatments to start soon.

REPLY

To everyone coming into this chat. It is specifically about Smoldering Multiple Myeloma (SMM). If you were looking for answers on other diagnosis, there are form chats specific to those. Please keep crosstalk to a minimum.
Thank you.

REPLY

For all Smoldering Multiple Myeloma (SMM) diagnosis, did your BMB show any gene mutations or Chromosomes deletions?

REPLY
Profile picture for salma5k @salma5k

@dmdinapoli81 Kappa is high at 227.9 mg/dL with ratio at 15.19 mg/L

Jump to this post

@salma5k i am lambda high
Total serum:
Lambda 631 mg/dl
Kappa < 35 mg/dl
Flc from bmb less than 0.1

REPLY
Profile picture for DMD81 @dmdinapoli81

To everyone coming into this chat. It is specifically about Smoldering Multiple Myeloma (SMM). If you were looking for answers on other diagnosis, there are form chats specific to those. Please keep crosstalk to a minimum.
Thank you.

Jump to this post

@dmdinapoli81
Isn’t “crosstalk” the purpose?

REPLY
Please sign in or register to post a reply.