Brinsupri follow-up

Is anybody taking Brinsupri who is colonized with pseudomonas? If so, please share how you are doing and any side effects. Thank you.

Sorry but I left that out. I am also colonized with pseudomonis. For that my ID doc has an every other month routine. During the month I am medicating I nebulize 1ml of colistamethate every other day. And on the days I'm not nebulizing I take cipro 250 mg. And I do seem to be coughing up less lung crap at this time.

@gctaylor1 Thanks for posting these photos. I use prophylactically, especially in the winter, AmLactin Foot Repair Cream with 15% Lactic Acid AHA on my feet to ward off any potential thickening of skin, as I am also on Brinsupri (3+ months, so far no side effects except for feeling better, less coughing, less phlegm, better sleep, more energy!)

Because of the possible side effects on gums, I floss every day and use a recommended rinse after brushing/flossing, which I swish for 30 seconds before spitting out. The hygienist gave me a refresher on flossing, which I'm glad she did because I wasn't doing it correctly.

@mpowers501
What do you mean by during the month I am medicating? Are you referring to Brinsupri?

Brinsupri Update! I started Brinsupri (10 mg) 3 weeks ago on thanksgiving day. Not sure what is going on but I feel much better!!! I was really dragging prior to starting...I am battling Bronchiectasis, weak heart (30 ejection fraction, and neuropathy (caused by Linezolid)! I was extremely short of breath and had zero energy. I am still sob but not as bad as before. My coughing is not as bad as it was prior, and I may be coughing up slightly less lung crap. I have had no side effects up to now and can actually do some things around the house. Hopefully my improvement will continue. Thank you Brinsupri!!!

PS: First time I saw SOB in my records I wondered what I had done to offend those people!!

Is anybody taking Brinsupri who is colonized with pseudomonas? If so, please share how you are doing and any side effects. Thank you.

@melinda561
My lungs are colonized with pseudomonas & aspergillus. Been on brinsupri since 10-1-25. Mucus much clearer, thinner, almost transparent & not as copious or thick & yellow like it used to be. I posted about my recent illness regarding total different reaction being on brinsupri vs before taking it. Time will tell.

Is anybody taking Brinsupri who is colonized with pseudomonas? If so, please share how you are doing and any side effects. Thank you.

@robot I finished 2 week course of IV cefepime 10/16. November sputum showed rare pseudomonas. ID said to hold off on BRINSUPRI as she may treat pseudomonas again. I have an appointment 2/2/26. Brinsupri was approved for me and I’ve been hesitant because of pseudomonas flare up. Thanks for your response.