Tymlos success?

Yes, absolutely. I went from -3.0 to -2.0 in under a year. You are starting at a lower level, it's true, but if you can get to -3.0, then there's some light at the end of the tunnel. Will you be getting a DEXA at the one-year mark? Did your doctor get baseline measurements for P1NP and CTX before you began?

Yes! Yes! Yes! In May of 2024 my scores were as follows:

AP Spine L 1-4 -3.1
Left femur total -3.0
Left femur neck -2.8

A year later, in 2025
AP Spine L 1-4 -1.8
Left femur total -2.4
Left femur neck -2.2

So yes, I have gone from osteoporosis to low bone mass/osteopenia.
Just stick with it. Two years will go by quickly and you will be glad you did it.
My doctor said he has never seen such drastic results in such a short period of time.

I will finish my two years in April of 2026 and am hopeful that my numbers will be even better in May of 2026 when I have my next Dexa Scan. I'll let you know.

Keep us up to date on your progress.

Hi,

Does anybody know the criteria for Tymlos in Ontario, Canada?

I'm 56 and my spine score is the same. I don't see an endocrinologist until January. I'm really hoping they put me on something that builds bone faster, but I'm in BC and they have certain criteria that I may not meet :+(

Hi! I’m 63 and had dexa score of negative 3.2 in my spine. I am active and in good shape so it was a complete shock. I started Tymlos a week ago and far so good but I am most concerned with the long term side effects and the fact that I will be on meds for the next 20 plus years. I’m wondering if Tymlos was a bad decision given that it’s only been around for eight years. I can still go off it. Just wondering if anyone has long term experience with Tymlos or other anabolic medications and what the course of treatment was.

@gowalking Do you know if Tymlos coats the bone to appear to have increased density in a DEXA scan like some of the other bone meds?

@rileyf Tymlos is an excellent medication based on research so far. I have been on it 14 months now with small increases in both my lumber spine and hip. I would encourage you to stay with it, unless you are experiencing significant side effects. K

@adam08
Thank you for your reply. I’ve only been on Tymlos for 10 days and question my decision to take it constantly!

@rileyf Given you have osteoporosis and a need to strengthen your bones, it is an excellent choice I think.

@rileyf Hello. My spinal score was -3.6...shocked, but not shocked, since I have had back pain for years, though without any fracture. I am 77, and the endocrinologist advised Tymlos, since I need to build bone, rather than just slow the loss. I had had a possible TIA, so Evenity was not an option, nor was Forteo. I took Tymlos for a month, and had an array of side effects, many of which eased or stopped over time, but some came later, and were significant enough to make me stop the drug . (Terrible fatigue and leg pains every evening, and the return of frequent headaches). Many people obviously have little or none of these, so I am not hear to say anything meant to be a generalized truth. But I do think that risk and benefit always need to be weighed, but especially if one is older. For me, to take a drug that would have me feeling like that for an indefinite time (two years??) was not something I am willing to do. I do not minimize the seriousness of my osteoporosis, and am exploring other options, and taking extra precautions. I don't know if this helps at all. I just feel strongly that each individual's overall health and stage of life need to be key factors here. It is also disturbing to me that doctors can disagree so widely on this subject. As a retired nurse, it seems that there should be more uniform guidelines by now. Wishing you success on whatever path you choose.