Hello everyone, I’m starting my ADT at the end of the week, I’m an active 73 years old I eat what I feel it’s a relatively healthy diet and regularly exercise however never really lost a lot of weight aside from heavy lifting no muscular physique or six pack either as I got older I lightened the weights and been boing more cardio ( Bulgarian bag kickboxing things like that) the weight just doesn’t come off and I do have a pouch I’m 67” and 185 now my concern is starting ADT most likely from what I read, I will gain weight and loose muscle so for you that have similar problem what it’s the answer, thanks for the help
Hello everyone, I’m starting my ADT at the end of the week, I’m an active 73 years old I eat what I feel it’s a relatively healthy diet and regularly exercise however never really lost a lot of weight aside from heavy lifting no muscular physique or six pack either as I got older I lightened the weights and been boing more cardio ( Bulgarian bag kickboxing things like that) the weight just doesn’t come off and I do have a pouch I’m 67” and 185 now my concern is starting ADT most likely from what I read, I will gain weight and loose muscle so for you that have similar problem what it’s the answer, thanks for the help
I'm 73, 68" and 206, up from 191 during treatment. With Testosterone 0, metabolism slows and calorie consumption has to drop or weight rises. That, combined with stress eating and struggling while moving toward plant-based sugarless diet, are causing my weight gain. Weight/resistance exercises seem to be key in reducing muscle loss, and exercise helps combat fatigue.
I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
Well before starting ADT (Eligard), my medical oncologist advised me about the possible and likely side-effects of hormone therapy (including weight gain due to the effects on metabolism), and how to minimize/avoid them.
So, I started a robust weightlifting and cardio program, as well as significantly modified my diet before the first injection. As a result, I lost 45 pounds during the 9 months the Eligard was in my system. (That crisis now past, I’ve put back on 20 of those lost 45 pounds…..hoping to maintain…..)
Are you tracking your caloric intake and calorie usage? Despite the decreased appetite and “eating like a bird,” you also mention “decreased activity”; it’s still often about a net increase in calories that results in weight gain.
GLP-1 medications work by mimicking your natural GLP-1 hormone to regulate blood sugar and promote weight loss by helping you feel fuller longer and reducing your appetite - but you already indicate that you’re not eating because you’re “just not hungry.”
I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
I agree with all that @brianjarvis said - however GLP-1 meds give two prong punch !
Yes, they slow digestion and promote satiety but the second equally important effect is stimulation of more insulin production and regulation of glucose metabolism.
Since ADT directly slows and effect glucose metabolism , GLP could give @thoffman6709 nice contra effect.
For some people who develop really slow metabolism and naturally have low muscle mass, exercise can help but not to the extent that is needed.
Gain of whooping 35 pounds in 4 months with no increase in food intake is extraordinary and points to metabolic problem. I am not a doctor, but perhaps GLP can really help in this case and GLP has other benefits beside weight loss so if it was me, I would try it.
I agree with all that @brianjarvis said - however GLP-1 meds give two prong punch !
Yes, they slow digestion and promote satiety but the second equally important effect is stimulation of more insulin production and regulation of glucose metabolism.
Since ADT directly slows and effect glucose metabolism , GLP could give @thoffman6709 nice contra effect.
For some people who develop really slow metabolism and naturally have low muscle mass, exercise can help but not to the extent that is needed.
Gain of whooping 35 pounds in 4 months with no increase in food intake is extraordinary and points to metabolic problem. I am not a doctor, but perhaps GLP can really help in this case and GLP has other benefits beside weight loss so if it was me, I would try it.
@surftohealth88 In recent years, they’ve opened up GPL-1 medications not just for diabetes and morbid obesity, but also for general weight loss.
Yes, as you point out the second equally important effect is stimulation of insulin production and lowering of glucose levels — and that will make him even “less hungry” (if that’s possible).
I’d be sure to ask my doctor if it was appropriate (especially if I was already “eating like a bird” due to hormone therapy).
@surftohealth88 In recent years, they’ve opened up GPL-1 medications not just for diabetes and morbid obesity, but also for general weight loss.
Yes, as you point out the second equally important effect is stimulation of insulin production and lowering of glucose levels — and that will make him even “less hungry” (if that’s possible).
I’d be sure to ask my doctor if it was appropriate (especially if I was already “eating like a bird” due to hormone therapy).
Satiety with GLP is effected more by slowing digestion and effecting brain centers for hunger than through glucose control - it happens both ways.
This patient was offered GLP by his doctor - so I guess they discussed it already. GLP medications show also some promise in cancer treatments and prevention so there could be multiple benefits.
I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
Yes. ADT changes your metabolism. Weight management, so that what you ate before may cause weight gain now. It's a tough one.
I lost 40 lb in hospital from post-surgical complications, then gained it all back (plus a little more) when my appetite finally returned a few months later.
I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
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Saying a prayer for you Brother. Onward and upward!
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1 ReactionI'm 73, 68" and 206, up from 191 during treatment. With Testosterone 0, metabolism slows and calorie consumption has to drop or weight rises. That, combined with stress eating and struggling while moving toward plant-based sugarless diet, are causing my weight gain. Weight/resistance exercises seem to be key in reducing muscle loss, and exercise helps combat fatigue.
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I have gained about 35 pounds since starting ADT. I'm 5'6" 72 years old, weigh 230 lbs. Mostly belly fat. Currently taking an ADT "holiday." Been off Lupron and Zytiga for about 4 months. Since starting ADT my physical activity has decreased, which I'm sure has contributed to the weight gain. At the same time my appitite and food intake has dramatically decreased. Just not hungry. I don't eat any crap food. My wife observes, "you eat like a bird." Given the dramatic decrease of food intake, I would expect to lose some weight, certainly not gain. Been thinking about talking to my doctor about taking some GLP-1 drugs.
Anyone else have a similar experience?
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1 ReactionWell before starting ADT (Eligard), my medical oncologist advised me about the possible and likely side-effects of hormone therapy (including weight gain due to the effects on metabolism), and how to minimize/avoid them.
So, I started a robust weightlifting and cardio program, as well as significantly modified my diet before the first injection. As a result, I lost 45 pounds during the 9 months the Eligard was in my system. (That crisis now past, I’ve put back on 20 of those lost 45 pounds…..hoping to maintain…..)
Are you tracking your caloric intake and calorie usage? Despite the decreased appetite and “eating like a bird,” you also mention “decreased activity”; it’s still often about a net increase in calories that results in weight gain.
GLP-1 medications work by mimicking your natural GLP-1 hormone to regulate blood sugar and promote weight loss by helping you feel fuller longer and reducing your appetite - but you already indicate that you’re not eating because you’re “just not hungry.”
Certainly something to discuss with your doctor.
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Like -
Helpful -
Hug
2 ReactionsI agree with all that @brianjarvis said - however GLP-1 meds give two prong punch !
Yes, they slow digestion and promote satiety but the second equally important effect is stimulation of more insulin production and regulation of glucose metabolism.
Since ADT directly slows and effect glucose metabolism , GLP could give @thoffman6709 nice contra effect.
For some people who develop really slow metabolism and naturally have low muscle mass, exercise can help but not to the extent that is needed.
Gain of whooping 35 pounds in 4 months with no increase in food intake is extraordinary and points to metabolic problem. I am not a doctor, but perhaps GLP can really help in this case and GLP has other benefits beside weight loss so if it was me, I would try it.
@surftohealth88 In recent years, they’ve opened up GPL-1 medications not just for diabetes and morbid obesity, but also for general weight loss.
Yes, as you point out the second equally important effect is stimulation of insulin production and lowering of glucose levels — and that will make him even “less hungry” (if that’s possible).
I’d be sure to ask my doctor if it was appropriate (especially if I was already “eating like a bird” due to hormone therapy).
@brianjarvis
Satiety with GLP is effected more by slowing digestion and effecting brain centers for hunger than through glucose control - it happens both ways.
This patient was offered GLP by his doctor - so I guess they discussed it already. GLP medications show also some promise in cancer treatments and prevention so there could be multiple benefits.
Yes. ADT changes your metabolism. Weight management, so that what you ate before may cause weight gain now. It's a tough one.
I lost 40 lb in hospital from post-surgical complications, then gained it all back (plus a little more) when my appetite finally returned a few months later.
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3 Reactions@thoffman6709, I moved your question to this related discussion:
- Weight gain: How do you control weight gain on hormone therapy (ADT)?https://connect.mayoclinic.org/discussion/weight-gain-4/
Also see this related discussion:
- Can GLP-1 drugs like Ozempic be used when taking hormone treatment? https://connect.mayoclinic.org/discussion/can-glp-1-drugs-like-ozempic-be-used-when-taking-lupron-etc/
@thoffman6709, may I ask why the physical activities have dropped off? Fatigue due to treatment? Lack of interest? Life got in the way?