Anyone having issues with gaining weight after liver transplant?

Posted by grateful76 @grateful76, Dec 2, 2024

Good evening,
I hope everyone is doing well.
My liver transplant was in January 2023 and I have been doing well. The only issue I am having now is, with gaining weight. In 2023 I was loosing weight and could not add any pounds but in 2024 it’s opposite. Anyone having similar problems?
Thank you so much for being here and helping me to stay healthy.
Happy Holidays!!!

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Profile picture for Stephen B @stephenbrown

I've experienced weight gain as well. My liver transplant was June 27, 2025 at Mayo in Jacksonville. Since the transplant I am experiencing terrible cramps in my hands, forearms, legs, and feet. No one seems to know the definitive cause of these but it makes it difficult to walk and I have now employed a cane. I am trying to do some indoor walking since I can rest when I like rather than be stuck outside and unable to go further. Less exercise, coupled with (until very recently) 40 MG of prednisone and insulin injections likely have caused the weight gain. I look forward to getting better and getting this weight back off.

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@stephenbrown Hi Stephen. I too have had cramps in my hands, legs and feet since my transplant but not nearly as bad as yours. They are there but not bad enough to bring it up to Mayo or local docs. But I think for me it may be do to me no longer having a galbladder due to the transplant .
And resulting from that water / liquids passing through me more quickly and me not staying sufficiently hydrated. Just a guess on my similar issue. Hoping it gets better when your off the prednisone for a while. Best of luck . (--:

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Profile picture for pgruetz @pgruetz

@stephenbrown
I didn’t feel remotely good for 2 years, swimming might help just walking in a pool does wonders, my feet have never been the same and the drugs didn’t do anything so I live with it, good luck on your recovery it’s a year at least so be patient

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@pgruetz I've heard that I should give it a year. And, I am certainly working to be patient. Sometimes, I'm just sick and tired of being sick and tired; yet still grateful for this gift.

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Profile picture for craigcraig @craigcraig

@stephenbrown Hi Stephen. I too have had cramps in my hands, legs and feet since my transplant but not nearly as bad as yours. They are there but not bad enough to bring it up to Mayo or local docs. But I think for me it may be do to me no longer having a galbladder due to the transplant .
And resulting from that water / liquids passing through me more quickly and me not staying sufficiently hydrated. Just a guess on my similar issue. Hoping it gets better when your off the prednisone for a while. Best of luck . (--:

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@craigcraig

That's a great thought nobody has mentioned to me (the water issue). I work to stay hydrated every day, mostly drinking only water, diet soda, tea, and one cup of coffee each day. I appreciate your response.

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Profile picture for Stephen B @stephenbrown

@pgruetz I've heard that I should give it a year. And, I am certainly working to be patient. Sometimes, I'm just sick and tired of being sick and tired; yet still grateful for this gift.

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@stephenbrown I wasn’t too patient and went back to worm after 6 months as a plumber and got injured so I recommend recover at least a year

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Profile picture for Stephen B @stephenbrown

I've experienced weight gain as well. My liver transplant was June 27, 2025 at Mayo in Jacksonville. Since the transplant I am experiencing terrible cramps in my hands, forearms, legs, and feet. No one seems to know the definitive cause of these but it makes it difficult to walk and I have now employed a cane. I am trying to do some indoor walking since I can rest when I like rather than be stuck outside and unable to go further. Less exercise, coupled with (until very recently) 40 MG of prednisone and insulin injections likely have caused the weight gain. I look forward to getting better and getting this weight back off.

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@stephenbrown I am six years out from my liver transplant - I am only taking tacromilis as far as prescriptions related to the transplant.. my Dr has me taking magnesium since the transplant and up until the last year it was part of my blood work. He told me at my last appointment I can reduce the amount - there were times my blood work results showed very low magnesium and during those times I experienced leg cramps th and fatigue. Just thought I would mention it. I would say the first year there were a few hiccups I had gout a few times and had never had that before the transplant. I would say you’re doing really well considering it’s only been six months. Best to you !

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Profile picture for Stephen B @stephenbrown

@pgruetz I've heard that I should give it a year. And, I am certainly working to be patient. Sometimes, I'm just sick and tired of being sick and tired; yet still grateful for this gift.

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@stephenbrown I understand that ! It is such a gift that I almost felt guilty bringing anything up if I did not feel well. I was diagnosed with Alpha 1 that lead to the transplant everything happen so quickly. I did not realize all the our liver does for us until I was sick.

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Profile picture for Stephen B @stephenbrown

I've experienced weight gain as well. My liver transplant was June 27, 2025 at Mayo in Jacksonville. Since the transplant I am experiencing terrible cramps in my hands, forearms, legs, and feet. No one seems to know the definitive cause of these but it makes it difficult to walk and I have now employed a cane. I am trying to do some indoor walking since I can rest when I like rather than be stuck outside and unable to go further. Less exercise, coupled with (until very recently) 40 MG of prednisone and insulin injections likely have caused the weight gain. I look forward to getting better and getting this weight back off.

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@stephenbrown
Hi Steven. I haven’t experienced muscle cramping but did have serves joint pain in every joint. Not sure if it’s a side effect from the anti rejection meds or from my osteoporosis medication. I also have developed neuropathy quite significantly in my feet and calves. My PCP says there are often unexplainable side effect from anesthesia, especially following a lengthy It didn’t start until about 4 months following my surgery (August 24). I just got rid of my treadmill and am looking into an exercise bike for the days I can’t walk well. Hang in there. I have hope that I will win the battle with my weight gain. Slow and steady. So grateful that I am still here to have these annoyances. Wishing you the best of luck.

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My transplant is 8 weeks ago

And my weight is down 50 lbs. I get around just fine but food is just now starting to taste good. Liver transplant.
Anyone else have this problem

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Hello,
You are not alone.
I know exactly what you are talking about. My liver Transplant was on September 2020 and had rejection on July 2021. I am not proud saying this but I was 245 pounds before 2020 and by July 2021 I was 133 and happy.
It didn’t last. Now in 2025 I am back to 190. My hepatologist told me that the anti-rejection medications can do that.
Please consult your doctor so you can be informed and at ease.
Good luck. Be blessed

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Profile picture for chuckhorse @chuckhorse

My transplant is 8 weeks ago

And my weight is down 50 lbs. I get around just fine but food is just now starting to taste good. Liver transplant.
Anyone else have this problem

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@chuckhorse
Yes. I just told someone else in this chat the same thing.
After being 245 lbs. before liver transplant and rejection 10 months after I was 133 lbs.
Food and I didn’t get along.
It will pass. You will get your tastebuds back in no time. It gets better every day and one step at a time.
Be well and be blessed.

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