@catken0701 Welcome to Connect. I have also had a bad reaction to a steroid spinal injection. I think it was an allergic reaction to polyethylene glycol that was likely an ingredient in the injection. I have had another instance of chronic hives after breaking my ankle and receiving titanium plates. I had them removed and that cleared up. I am also a spine surgery patient and elected a single level fusion without hardware.

I have also at one time had weird patches of goose bumps on my legs. I think it was due to a bulging spinal disc in lumbar. I had had a whiplash and that area would crack if I twisted. I did at times have some sciatic pain. That was early on. Eventually, I developed spinal cord compression in my neck and had a fusion of C5/C6. I haven’t had that weird goosebumps rash in years.

I’m not sure exactly what you are describing in your spine. Do you have either spinal cord compression or compression of spinal nerve roots? Did the immune issues derail consideration of structural spinal issues?